Results 51 to 60 of about 9,605,234 (296)

Structured early childhood education exposure and childhood cognition – Evidence from an Indian birth cohort

Scientific Reports
Experiences in early childhood form the bedrock of future human potential. In impoverished settings, structured early childhood education (ECE) in preschool years can augment overall childhood and later human abilities.
Beena Koshy, Manikandan Srinivasan, Rangan Srinivasaraghavan, Reeba Roshan, Venkata Raghava Mohan, Karthikeyan Ramanujam, Sushil John, Gagandeep Kang   +7 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Regeneration Of Thermally Recycled Glass Fibre For Cost-Effective Composite Recycling : Overview of the ReCoVeR projects [PDF]

, 2014
Global production of composite materials in 2015 will significantly exceed 10 million tons. Glass fibre reinforced composites account for more than 90% of all the fibre-reinforced composites currently produced.
Thomason, James, Saez Rodriguez, Eduardo, Nagel, Ulf, Kao, Chih-Chuan, Yang, Liu, Jenkins, Peter   +5 more
core   +3 more sources

Cost-Effective with Silver Alloys in Water

Journal of Pure and Applied Microbiology, 2017
The aim of this study is to determine the effect of Silver and electrical current in preventing the growth of bacteria in drinking water to keep water safe.
Amal Abdulaziz Aljuraifani, Azzah Ibrahim Alghamdi   +1 more
doaj   +1 more source

Sulfasalzine in the management of pure axial spondyloarthritis: Need to have a relook!

Indian Journal of Rheumatology, 2020
The role of sulfasalazine in pure axial spondyloarthritis (axial SpA) is claimed to be almost non-existent, due to very low-quality evidence from available literature.
Subramanian Shankar, Arun Hegde
doaj   +1 more source

Meaningfulness of Academic Migrants’ Education, Its Assessment and Modeling on It-based Technologies [PDF]

Экономика региона, 2016
The article is devoted to the relevant problems of educational migration flows both in the real and virtual environment. The article discusses the positive and negative experience with virtual platforms in Russia and abroad.
Tamara Vladimirovna Kuprina, Jaroslav Kultan, Tomáš Kozík, Svetlana Mikhaelovna Minasyan   +3 more
doaj   +1 more source

Effectiveness Is the Key to Cost-Effectiveness [PDF]

Circulation, 2013
Health care spending has risen faster than the rest of the United States economy for the past several decades, and is now swamping federal and state government budgets. The rising cost of health care has important consequences: either spending on other programs (eg, education, public safety, and infrastructure) must be reduced, or taxes must rise, or ...
openaire   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source