Results 111 to 120 of about 2,826,501 (343)
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
Effectiveness Is the Key to Cost-Effectiveness [PDF]
Circulation, 2013 Health care spending has risen faster than the rest of the United States economy for the past several decades, and is now swamping federal and state government budgets. The rising cost of health care has important consequences: either spending on other programs (eg, education, public safety, and infrastructure) must be reduced, or taxes must rise, or ...
openaire +3 more sources
Cost Effectiveness and Resource Allocation, 2010 Background Total hip replacement surgery places a considerable financial burden on health services and society. Given the large number of hip prostheses available to surgeons, reliable economic evidence is crucial to inform resource allocation decisions.
Mugford Miranda +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Delivering diabetes education through nurseled telecoaching : cost-effectiveness analysis [PDF]
, 2016 Background : People with diabetes have a high risk of developing micro-and macrovascular complications associated with diminished life expectancy and elevated treatment costs. Patient education programs can improve diabetes control in the short term, but
Aertgeerts, Bert +5 more
core +3 more sources
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
To what extent does recurrent government health expenditure in Uganda reflect its policy priorities?
Cost Effectiveness and Resource Allocation, 2010 Background The National Health Policy 2000 - 2009 and Health sector strategic plans I & II emphasized that Primary Health Care (PHC) would be the main strategy for national development and would be operationalized through provision of the minimum health ...
Nabyonga-Orem Juliet, Mugisha Frederick
doaj +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Costs, cost-effectiveness, and context
The American Journal of Clinical Nutrition, 2022 Reina Engle-Stone, Katherine P Adams
openaire +2 more sources
Participant Bidding Enhances Cost Effectiveness [PDF]
A multitude of design decisions influence the performance of voluntary conservation programs. This Economic Brief is one of a set of five exploring the implications of decisions policymakers and program managers must make about who is eligible to receive
Johansson, Robert C.
core +1 more source