Results 81 to 90 of about 3,099,670 (313)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Biosimilar medicines and cost-effectiveness

ClinicoEconomics and Outcomes Research, 2011
Steven SimoensResearch Centre for Pharmaceutical Care and Pharmaco-economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Leuven, BelgiumAbstract: Given that biosimilars are agents that are similar but not identical to the ...
Steven Simoens
doaj  

National cost study versus hospital cost accounting for organ recovery cost assessment in a French hospital group

Cost Effectiveness and Resource Allocation, 2018
Background The choice of cost data sources is crucial, because it influences the results of cost studies, decisions of hospital managers and ultimately national directives of policy makers.
Abdelbaste Hrifach, Christell Ganne, Sandrine Couray-Targe, Coralie Brault, Pascale Guerre, Hassan Serrier, Hugo Rabier, Gwen Grguric, Pierre Farge, Cyrille Colin   +9 more
doaj   +1 more source

A cost utility and cost effectiveness analysis of different oral antiviral medications in patients with HBeAg-Negative chronic hepatitis B in Iran: an economic microsimulation decision model [PDF]

, 2016
Background: Although hepatitis B infection is the major cause of chronic liver disease in Iran, no studies have employed economic evaluations of the medications used to treat Iranian patients with chronic hepatitis B (CHB).
Alavian, Seyed Moayed, Javanbakht, Mehdi, Kebriaeezadeh, Abbas, Keshavarz, Khosro, Keshvari, Maryam, Lotfi, Farhad, Meshkini, Amir Hashemi, Nikfar, Shekoufeh, Rezaei Hemami, Mohsen, Sari, Ali Akbari   +9 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Enhancing the comparability of costing methods: cross-country variability in the prices of non-traded inputs to health programmes

Cost Effectiveness and Resource Allocation, 2006
Background National and international policy makers have been increasing their focus on developing strategies to enable poor countries achieve the millennium development goals.
Evans David B, Adam Taghreed, Johns Benjamin   +2 more
doaj   +1 more source

Pressure relieving support surfaces (PRESSURE) trial : cost effectiveness analysis [PDF]

, 2006
Objective To assess tire cost effectiveness of alternating pressure mattresses compared with alternating pressure overlays for the prevention of pressure ulcers in patients admitted to hospital.
Cranny, Gillian, Cullum, Nicky, Grp, PRESSURE Trial, Hawkins, Kim, Iglesias, Cynthia, Mason, Su, Nelson, E Andrea, Nixon, Jane, Phillips, Angela, Torgerson, David   +9 more
core   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Cost-Effectiveness Analysis Terapi Antibiotik Seftriakson Dan Sefotaksim Pada Pasien Tifoid Di RSUD Dr. M.M Dunda Limboto [PDF]

, 2017
Tifoid merupakan penyakit infeksi yang disebabkan oleh bakteri Salmonella typhi dan telah banyak menginfeksi masyarakat baik di perkotaan maupun pedesaan.
Tuloli, T. S. (Teti)
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source