Results 61 to 70 of about 1,825,200 (294)

Cost Estimation of Detection of Peripheral Arterial Disease by Pulse Oximeter among Diabetic Patients and Assessing Its Feasibility at Family Health Centers in Alexandria

Journal of High Institute of Public Health
Background: Peripheral arterial disease (PAD) is more common in diabetic patients as compared to non-diabetic people, with a high risk of lower limb ischemia, ulcer, and amputation.
Nourhan R. Mostafa , Amal E. Khairy, Manal R. Koura, Shaymaa S. Habib, Noha S. Moustafa   +4 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

A price-determining model for industrial “technology-push” innovations [PDF]

Innovative Marketing
Type of the article: Research Article AbstractThe complexity of industrial markets in the Fourth Industrial Revolution necessitates new pricing approaches for R&D outcomes.
Nataliya Chukhray , Oleksandra Mrykhina, Khrystyna Bespaliuk, Andrii Chukhrai   +3 more
doaj   +1 more source

Use of artificial intelligence for estimating cost of integral bridges

Građevinar, 2021
Estimation of costs is important in every phase of realisation of construction projects. However, the influence of cost estimation is the highest in early phases as it is then that the decision about accepting the job or withdrawing from the project is ...
Željka Beljkaš, Miloš Knežević
doaj   +1 more source

Calculating the Expected Value of Sample Information using Efficient Nested Monte Carlo: A Tutorial [PDF]

, 2018
Objective: The Expected Value of Sample Information (EVSI) quantifies the economic benefit of reducing uncertainty in a health economic model by collecting additional information.
Baio, Gianluca, Heath, Anna
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Spacecraft cost estimation [PDF]

Spacecraft subsystem cost ...
Finnegan, W. P., Stone, C. A.
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source