Results 81 to 90 of about 1,812,913 (288)

Kernel alternatives to aproximate operational severity distribution: an empirical application [PDF]

open access: yes, 2011
The estimation of severity loss distribution is one the main topic in operational risk estimation. Numerous parametric estimations have been suggested although very few work for both high frequency small losses and low frequency big losses.
Di Pietro, Filippo   +2 more
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Estimating the cost of major ongoing cost plus hardware development programs [PDF]

open access: yes
Approaches are developed for forecasting the cost of major hardware development programs while these programs are in the design and development C/D phase.
Bush, J. C.
core   +1 more source

Multi-Bernoulli Sensor-Control via Minimization of Expected Estimation Errors

open access: yes, 2015
This paper presents a sensor-control method for choosing the best next state of the sensor(s), that provide(s) accurate estimation results in a multi-target tracking application.
Bab-Hadiashar, Alireza   +2 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Impact of Using an Exchange Model (EM) to Support the Early Assessment Process of Industrialized Timber Projects

open access: yesBuildings
Standardized information on the processes and requirements for information exchanges is critical to ensure accurate cost estimations. However, traditional methods based on 2D information lack the standardization and information required for efficient and
Claudia Rojas   +5 more
doaj   +1 more source

Successful Control of Major Project Budgets

open access: yesAdministrative Sciences, 2016
This paper differs from scientific papers describing current research. In line with the theme of this special issue, it challenges conventional risk management practice against the background of former research results successfully finished decades ago ...
Steen Lichtenberg
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Software Development Cost Estimation Methods [PDF]

open access: yesComputer Science, 2003
Early estimation of project size and completion time is essential for successful project planning and tracking. Multiple methods have been proposed to estimate software size and cost parameters.
Bogdan Stepien
doaj  

Liquid composite molding reproducibility in real-world production of fiber reinforced polymeric composites: a review of challenges and solutions

open access: yesAdvanced Manufacturing: Polymer & Composites Science, 2019
Liquid composite molding (LCM) suffers from multiple factors that contribute to pronounced uncertainty of process characteristics. This results in compromised reproducibility which is associated to high scrap or the unpredictable behavior of approved ...
Spiridon Konstantopoulos   +4 more
doaj   +1 more source

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