Results 71 to 80 of about 1,566,854 (312)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Benchmarking and incentive regulation of quality of service: an application to the UK electricity distribution utilities

open access: yes, 2004
Quality of service has emerged as an important issue in post-reform regulation of electricity distribution networks. Regulators have employed partial incentive schemes to promote cost saving, investment efficiency, and service quality.

core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

COVID-19, Accruals Quality and Cost of Debt [PDF]

open access: yesمطالعات تجربی حسابداری مالی
The accounting information quality and its relationship with financing decision-making is one of the important issues that attract interest from researchers.
Abbas Aflatooni   +2 more
doaj   +1 more source

Oregon Department of Environmental Quality's low-cost air quality SensOR

open access: yes, 2019
A new lower-cost air quality monitor developed by the Oregon Department of Environmental Quality's Laboratory will allow the agency to provide timely air quality information at more locations throughout the state.This archived document is maintained by ...

core  

Effectiveness and cost-effectiveness of community singing on mental health-related quality of life of older people: randomised controlled trial [PDF]

open access: yes, 2015
Background As the population ages, older people account for a greater proportion of the health and social care budget. Whereas some research has been conducted on the use of music therapy for specific clinical populations, little rigorous research has ...
Skingley, A.   +7 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

A General Approach of Quality Cost Management Suitable for Effective Implementation in Software Systems [PDF]

open access: yes
Investments in quality are best quantified by implementing and managing quality cost systems. A review of various opinions coming from practitioners and researchers about the existent quality cost models reveals a set of drawbacks (e.g.
Stelian BRAD
core  

CSU-Agricultural-Water-Quality-Program/low-cost-iot-water-sampler: Initial Public Release

open access: yes, 2023
<h1>Initial release of the AWQP Low-Cost IoT Water Sampler, Version 1.10</h1> <p>A low-cost, automated water sampler (LCS) with Internet of Things (IoT) technology for scalable, near-real-time water quality research developed by the ...
AJ Brown
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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