Results 41 to 50 of about 307,587 (262)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Association Between Copayments and Attendance in Cardiac Rehabilitation: A Nationwide Analysis From the AACVPR Registry

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Improving cardiac rehabilitation (CR) participation is a national priority. This study examines the prevalence and cost of copays and their relationship with CR attendance and dropout.
Sumsen Thapa, Maryam Naser, Michel Farah, Yu Zhang, George Howard, Tara Lagu, Peter K. Lindenauer, Quinn R. Pack   +7 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Patient Perspectives on Health Insurance Design: A Mixed-Methods Analysis

Journal of Market Access & Health Policy
There remains a persistent lack of patient-centered evidence on insurance reform and real-world experiences of patients with chronic disease. This study gathered insights around insurance design from chronic disease beneficiaries.
Bridget Doherty, Kimberly Hooks, Ulrich Neumann, Wesley Peters, Steven Zona, Lisa Shea   +5 more
doaj   +1 more source

Is Shapley Cost Sharing Optimal? [PDF]

Games and Economic Behavior, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Shahar Dobzinski, Aranyak Mehta, Tim Roughgarden, Mukund Sundararajan   +3 more
openaire   +2 more sources

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Time-Sharing Trading Price Formation Mechanism and Model of China’s Mid to Long-Term Electricity Market

Zhongguo dianli, 2023
The time-sharing trading of mid to long-term electricity market is one of the important reform measures for China's electricity market. Aiming at the unreasonable and imperfect problem of current time-sharing trading price formation mechanism, a novel ...
Shanshan HUANG, Ze YE, Mai LUO, Lei CHEN, Wen WEI, Jun YAO   +5 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

R&D Cost Sharing of Intelligent Upgrading of Photovoltaic Power Stations

Systems
The intelligent upgrading of photovoltaic (PV) power stations can improve their power-generating capacity, reduce operation and maintenance (O&M) costs, and effectively conserve energy and reduce emissions.
Yibo Hu, Yuhan Chen, Li Hou
doaj   +1 more source