Results 131 to 140 of about 15,086 (322)

Evolution of the Nuss procedure for the repair of Pectus Excavatum: Our experience. [PDF]

open access: yes, 2016
The aim of this study is to collect the variables of the Nuss procedure developed by experts in this technique around the world and present their advantages and disadvantages compared to the original description of the Nuss procedure.
GOULI, MARIA
core  

Brachyury‐Activated Fucoidan Hydrogel Microspheres Rejuvenate Degenerative Intervertebral Discs Microenvironment

open access: yesAdvanced Science, EarlyView.
This study describes the creation of injectable Brachyury (Bry) mRNA‐loaded Fucoidan‐functionalized GelMA hydrogel microspheres (BLNP@GF). These microspheres efficiently suppress inflammation, enhance extracellular matrix (ECM) synthesis in degenerated nucleus pulposus cells, and mitigate intervertebral disc degeneration (IVDD) in rat models.
Yuhao Gong   +12 more
wiley   +1 more source

Establishment and characterization of chondrocyte cell lines from the costal cartilage of SV40 large T antigen transgenic mice [PDF]

open access: bronze, 2001
Eiichiro Kitaoka   +7 more
openalex   +1 more source

Dual‐Modular Hydrogel Microparticles with Precision‐Modulation of Inflammatory Microenvironment Dictate Full‐Thickness Cartilage Regeneration for Osteoarthritis Repair

open access: yesAdvanced Science, EarlyView.
Cartilage injury is a prominent pathological hallmark of osteoarthritis. In this study, we developed a two‐modular hydrogel microparticle system wherein HMP‐A effectively targets the damaged area, while HMP‐B forms an efficient connection with HMP‐A on the cartilage surface.
Xinye Chen   +5 more
wiley   +1 more source

Rabbit articular cartilage defects treated with cultured costal chondrocytes (preliminary report) [PDF]

open access: yes, 2003
An attempt to repair articular cartilage defects by costal chondrocytes transplantation was made. A full-thickness defect in the rabbit's femoral patellar groove was artificially made.
Popko, Janusz   +4 more
core   +1 more source

β‐Mangostin Attenuates TET2‐Mediated DNA Demethylation of Prkcg in the Prevention of Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
β‐Mangostin alleviates intervertebral disc degeneration through dual modulation of macrophage polarization and the TET2‐Prkcg axis in nucleus pulposus cells. Abstract Intervertebral disc degeneration (IDD) induced lower back pain is a main cause of disability, resulting in a substantial workforce loss worldwide and placing a substantial burden on the ...
Xiangzhen Kong   +15 more
wiley   +1 more source

Targeting eRNA‐Producing Super‐Enhancers Regulates TNFα Expression and Mitigates Chronic Inflammation in Mice and Patient‐Derived Immune Cells

open access: yesAdvanced Science, EarlyView.
Targeting eRNAs from TNFα‐associated super‐enhancers with ASOs effectively reduces TNFα expression and inflammatory responses in both mouse models and patient‐derived immune cells. The conserved nature of these regulatory regions between species highlights the potential of eRNA‐targeted approaches as a therapeutic strategy for chronic inflammatory ...
Minjeong Cho   +12 more
wiley   +1 more source

AUGMENTATION RHINOPLASTY: 9TH COSTAL CARTILAGE GRAFT FOR STAGE III SADDLE NOSE DEFORMITY

open access: yesPakistan Armed Forces Medical Journal, 2018
Objective: To evaluate the results of 9th rib costal cartilage in the reconstruction of stage III saddle nose deformity. Study Design: Case series.
Rana Hassan Javaid   +2 more
doaj  

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