Results 141 to 150 of about 1,913 (224)

Intradiscal Mesenchymal Stromal Cell Therapy for the Treatment of Low Back Pain Due to Moderate‐to‐Advanced Multilevel Disc Degeneration: A Preliminary Report of a Double‐Blind, Phase IIB Randomized Clinical Trial (DREAM Study)

JOR SPINE, Volume 8, Issue 2, June 2025.
This phase IIB randomized controlled trial evaluated the safety and efficacy of intradiscal injections of autologous bone marrow‐derived mesenchymal stromal cells (BM‐MSCs) in patients with chronic low back pain from moderate‐to‐advanced multilevel disc degeneration.
Gianluca Vadalà, Fabrizio Russo, Cristiana Lavazza, Giorgia Petrucci, Luca Ambrosio, Silvia Budelli, Elisa Montelatici, Giuseppina Di Giacomo, Claudia Cicione, Veronica Tilotta, Giuseppe Francesco Papalia, Matteo Pileri, Amalia Bruno, Salvatore La Rosa, Emilio Carrino, Eliodoro Faiella, Massimiliano Carassiti, Lorenza Lazzari, Rocco Papalia, Vincenzo Denaro   +19 more
wiley   +1 more source

AMIC achieves sustained clinical improvement in isolated patellar cartilage defects over 5 years, correlating with MRI

Knee Surgery, Sports Traumatology, Arthroscopy, Volume 33, Issue 6, Page 2104-2113, June 2025.
Autologous matrix‐induced chondrogenesis achieves clinical and magnetic resonance imaging improvement over 5‐year patellar cartilage defects. Abstract Purpose To evaluate 5‐year postoperative clinical outcomes of autologous matrix‐induced chondrogenesis (AMIC) for isolated ICRS grade 3–4 patellar cartilage defects and correlate outcomes with magnetic ...
Nayana Joshi Jubert, Mercè Reverté Vinaixa, Irene Portas Torres, Daniel Moreno Martínez, Marcelo Casaccia, Marc Aguilar Garcia, Joan Pijoan Bueno, Enric Castellet Feliu, Joan Minguell Monyart   +8 more
wiley   +1 more source

Knee joint dislocations—Current epidemiology and treatment in Germany

Knee Surgery, Sports Traumatology, Arthroscopy, Volume 33, Issue 6, Page 2114-2121, June 2025.
Abstract Purpose Knee joint dislocations, though rare, present significant challenges due to potential complications like vascular and nerve damage, and are known to be often linked to sports injuries, accidents and obesity. This study aims to analyse the epidemiology, incidence and treatment approaches for knee dislocations in Germany from 2019 to ...
Johannes Weber, Dominik Szymski, Lorenz Huber, Josina Straub, Volker Alt, Julia Elisabeth Lenz   +5 more
wiley   +1 more source

Dysphagia After Pediatric Laryngotracheal Reconstruction—A Scoping Review

Laryngoscope Investigative Otolaryngology, Volume 10, Issue 3, June 2025.
Pediatric airway surgeries have the potential to negatively impact postoperative swallow function. This scoping review evaluated the literature describing swallowing function after common airway surgeries in children. ABSTRACT Objective To review swallowing outcomes after pediatric laryngotracheal reconstruction.
Noor Singh, Stephen R. Chorney, Romaine F. Johnson, Taylor B. Teplitzky   +3 more
wiley   +1 more source

Microsurgical Robotic System for Myringoplasty: Feasibility Study

Laryngoscope Investigative Otolaryngology, Volume 10, Issue 3, June 2025.
We evaluated a prototype of a new microsurgical robot designed for use in otology. The system was tested in a rabbit myringoplasty procedure, demonstrating its capability to perform microsurgery in narrow and deep regions. ABSTRACT Objective Otological surgery requires exceptional precision and advanced surgical skills, particularly for procedures ...
Tadao Yoshida, Masumi Kobayashi, Tomohito Okubo, Naoyuki Hatayama, Shun Otsuka, Kazuhito Wakana, Hirofumi Owaki, Yasuhiro Matsuda, Kei Mikami, Munekazu Naito   +9 more
wiley   +1 more source

Reconstructive rhinoplasty with costal cartilage grafting: A case report of relapsing polychondritis [PDF]

, 2019
Yun-Hae Lee, Hyungon Choi
openalex   +1 more source

Design and Characterization of Decellularized Caprine Liver Matrix Constructs for Liver Tissue Engineering

Macromolecular Materials and Engineering, Volume 310, Issue 6, June 2025.
This study develops decellularized caprine liver scaffolds, preserving ECM components like collagen and GAGs. The scaffolds are combined with Chitosan‐PVA hydrogels, optimized via FT crosslinking, thus exhibiting shear‐thinning behavior, enhanced mechanical properties, and biocompatibility, supporting HepG2 cell adhesion, proliferation, and hepatic ...
Supriya Bhatt, Jayanthi Krishnakumar, Kondepudi Lakshmi Mounica, Manasa Nune   +3 more
wiley   +1 more source

Bioengineered Nanozymes for Orthopedic Degenerative Diseases: From Catalytic Mechanisms to Multimodal Therapy

MedComm – Biomaterials and Applications, Volume 4, Issue 2, June 2025.
IDD and OA is caused by various mechanisms, creating a vicious cycle that impairs disc function. Nanozymes and nano‐enzyme delivery systems offer innovative therapies by targeting these underlying mechanisms, such as anti‐inflammatory therapy, ECM repair, cellular dysfunction and antioxidant therapy, providing a promising approach to restoring tissue ...
Lei Peng, Chen Yan, Honghao Song, Jiangang Shi, Kaiqiang Sun   +4 more
wiley   +1 more source

Resveratrol: Molecular Mechanisms, Health Benefits, and Potential Adverse Effects

MedComm, Volume 6, Issue 6, June 2025.
As a polyphenol substance with important potential, resveratrol has important potential in degenerative diseases, cardiovascular diseases, cancer, neurological diseases, etc. However, it is still necessary to pay attention to its bioavailability and potential adverse effects.
Zhuo‐qun Ren, Sheng‐yuan Zheng, Zhengcheng Sun, Yan Luo, Yu‐tong Wang, Ping Yi, Yu‐sheng Li, Cheng Huang, Wen‐feng Xiao   +8 more
wiley   +1 more source

The ‘C’ costal cartilage graft in reconstruction of the unilateral cleft lip nose

, 1981
Laurence A. Chait
openalex   +1 more source