Results 51 to 60 of about 5,884 (248)
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Un modelo eficiente para la financiación pública de la universidad: el caso español
Revista Facultad de Ciencias Económicas, 2007 El presente trabajo realiza una aproximación al uso de los recursos públicos destinados a la fi nanciación de las Instituciones de Educación Superior desde la perspectiva de la efi ciencia fi nanciera.
Leonor Mora Agudo +1 more
doaj
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Comparativa de resultados de rehabilitación energética para viviendas en función del grado de mejora
Informes de la Construccion, 2016 El objetivo del artículo es el estudio de viabilidad en mejoras de eficiencia energética a través del análisis del ahorro energético y de la inversión económica.
A. Pérez Fargallo +2 more
doaj +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Tiempos necesarios para la dispensación de recetas electrónicas en Galicia: necesidades y procesos
Farmacéuticos Comunitarios, 2012 OBJETIVOS Registrar el tiempo requerido para los procesos que componen el acto de dispensación de e-receta y su frecuencia, evaluar los costes directos de los procesos, describir los resultados negativos de la medicación (RNM) detectados, definir la ...
Casal Sánchez C, Losada Campa MJ
doaj
Economía Agraria y Recursos NaturalesLa Vespa velutina nigrithorax (V. velutina) es una especie invasora introducida en Europa en 2004 y extendida rápidamente con repercusiones en la apicultura, la salud o los servicios de polinización.
Ana Isabel García-Arias +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source