Results 61 to 70 of about 4,067,843 (298)

Crop Costs and Returns 2000

, 2000
Teagasc SubmissionThe Teagasc Crops Costs & Returns are intended as an indicative guide to crop margins; however land suitability, rotation, risk avoidance and husbandry skills must also be ...
O'Mahony, Jim
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Control de gestión para una red de pymes agroturísticas orientadas a la calidad territorial

Costos y Gestión, 2015
Varias pequeñas empresas agrarias, muchas de ellas familiares, se han asociado bajo el programa Cambio Rural INTA (Instituto Nacional de Tecnología Agropecuaria), que encuadrado en el Programa Federal de Apoyo al Desarrollo Rural Sustentable (ProFeDeR),
Regina Durán, Liliana Scoponi, Fabiana Casarsa, Marianela De Batista, Marina Cordisco, Veronica Piñeiro   +5 more
doaj  

EFECTOS AMBIENTALES Y SUS COSTOS EN EL TRÁNSITO HACIA LA VIRTUALIDAD ACADÉMICA

Costos y Gestión, 2020
Tendencias globales como la sostenibilidad de las prácticas organizativas, adhesión a estándares internacionales y reducción de residuos se perciben en las exigencias de la sociedad a través de la presión legislativa y la demanda de transparencia ...
Alejandra Narvarte, Alicia Inés Zanfrillo, María Antonia Artola   +2 more
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

El costo político en el cálculo del costo kilómetro del clúster transporte urbano colectivo de pasajeros

Costos y Gestión, 2020
El clúster de transporte urbano colectivo de pasajeros de ciudades de hasta 120.000 habitantes, es el objeto de análisis del presente trabajo a los efectos de determinar el costo kilómetro pasajero normalizado de dicho clúster.
Gladys Ferraro, Gustavo Metilli, Claudio Biset   +2 more
doaj  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Gregorio Coronel Troncoso

Costos y Gestión, 2020
Gregorio Coronel Troncoso Presidente Iapuco 1999 ...
Gregorio Coronel Troncoso
doaj  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source