Results 51 to 60 of about 6,843,897 (307)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

switching costs

, 2008
Switching costs arise when transactions, learning, or pecuniary costs are incurred by a user who changes suppliers (including for ‘follow-on’ or ‘aftermarket’ products such as refills and repairs). The ex post market power that switching costs give suppliers need not create inefficiencies, and early ‘bargain’ prices can compensate consumers for later ...
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Control de gestión para una red de pymes agroturísticas orientadas a la calidad territorial

Costos y Gestión, 2015
Varias pequeñas empresas agrarias, muchas de ellas familiares, se han asociado bajo el programa Cambio Rural INTA (Instituto Nacional de Tecnología Agropecuaria), que encuadrado en el Programa Federal de Apoyo al Desarrollo Rural Sustentable (ProFeDeR),
Regina Durán, Liliana Scoponi, Fabiana Casarsa, Marianela De Batista, Marina Cordisco, Veronica Piñeiro   +5 more
doaj  

EFECTOS AMBIENTALES Y SUS COSTOS EN EL TRÁNSITO HACIA LA VIRTUALIDAD ACADÉMICA

Costos y Gestión, 2020
Tendencias globales como la sostenibilidad de las prácticas organizativas, adhesión a estándares internacionales y reducción de residuos se perciben en las exigencias de la sociedad a través de la presión legislativa y la demanda de transparencia ...
Alejandra Narvarte, Alicia Inés Zanfrillo, María Antonia Artola   +2 more
doaj  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

El costo político en el cálculo del costo kilómetro del clúster transporte urbano colectivo de pasajeros

Costos y Gestión, 2020
El clúster de transporte urbano colectivo de pasajeros de ciudades de hasta 120.000 habitantes, es el objeto de análisis del presente trabajo a los efectos de determinar el costo kilómetro pasajero normalizado de dicho clúster.
Gladys Ferraro, Gustavo Metilli, Claudio Biset   +2 more
doaj  

Product Differentiation Costs and Global Competition [PDF]

, 2005
The growing competitive intensity on the markets determines the emergence of competition costs that are expressed at a corporate level and have implicit repercussions for the supply system.
Baldwin, C.Y., Brondoni, S.M., Calcagno, M., Cappelletti, M., Chamberlin, E. H., Corniani, M., Corniani, M., Gallinaro, S., Gallinaro, S., Garbelli, M.E., Garbelli, M.E., Gnecchi, Flavio, Golinelli, G.M., Lambin J.J., Lugli, G., Maggioni, V., Monden Y., Ohno, T., Piore, M.J., Porter, M.E., Rossano, L., Salvioni, D.M, Scicutella, M., Shingo, S., Taylor, F.W., Toffler, A.   +25 more
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Gregorio Coronel Troncoso

Costos y Gestión, 2020
Gregorio Coronel Troncoso Presidente Iapuco 1999 ...
Gregorio Coronel Troncoso
doaj