Results 91 to 100 of about 3,520,446 (404)

Virtual outreach: economic evaluation of joint teleconsultations for patients referred by their general practitioner for a specialist opinion [PDF]

, 2003
Objectives To test the hypotheses that, compared with conventional outpatient consultations, joint teleconsultation (virtual outreach) would incur no increased costs to the NHS, reduce costs to patients, and reduce absences from work by patients and ...
Barber, JA, Currell, R, Haines, A, Harrison, R, Jacklin, PB, Lewis, L, Parker, S, Roberts, JA, Thompson, SG, Virtual Outreach Project Grp, Wainwright, P, Wallace, P   +11 more
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Current Knowledge and Attitudes Concerning Cost-Effectiveness in Glaucoma Pharmacotherapy: A Glaucoma Specialists Focus Group Study. [PDF]

, 2020
Background:Rising healthcare costs motivate continued cost-reduction efforts. To help lower costs associated with open-angle glaucoma (OAG), a prevalent, progressive disease with substantial direct and indirect costs, clinicians need to understand the ...
Cioffi, George A, Feldman, Robert M, Feldman, Robert M, Liebmann, Jeffrey M, Weinreb, Robert N   +4 more
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Financing threatened species management: the costs of single species programmes and the budget constraint [PDF]

In New Zealand total annual funding allows 15 percent of the 2,400 threatened species to be targeted for management. Although management costs are crucial to a conservation organisation's ability to achieve its goals, estimates of costs are not usually ...
Cullen, Ross, Hughey, Kenneth F.D., Moran, Emma   +2 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Cost-Utility of Interventions in Patients with Carpal Tunnel Syndrome in a Universitary Hospital in Cali, Colombia

Revista Ciencias de la Salud, 2015
Introduction: Although there are several treatments for carpal tunnel syndrome (CTS), the efficiency of these has not evaluated in Colombia. Objective: Determine the incremental cost-utility ratio (ICUR) of medical and surgical treatment in patients with
César Augusto Guevara, Yuri Takeuchi
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Estimativa de custos diretos do Programa Municipal de Controle da Dengue de Goiânia-GO

Epidemiologia e Serviços de Saúde
OBJETIVO: estimar os custos do Programa Municipal de Controle da Dengue de Goiânia-GO, Brasil. MÉTODOS: estudo de custo de programa considerando períodos epidêmico (outubro/2009-abril/2010) e endêmico (maio-setembro/2010) de transmissão da doença, na ...
Sandra Maria dos Santos, Flúvia Amorim, Izaías de Araújo Ferreira, Giovanini Evelim Coelho, Alexander Itria, João Bosco Siqueira Junior, Cristiana Maria Toscano   +6 more
doaj   +1 more source

Epiemiologic Features and Hospitalization Cost of Burn Injuries in Iran Based on National Burn Registry; a Cross-sectional Study

Archives of Academic Emergency Medicine, 2019
Introduction: Burn is one of the most common causes of injury in the world. The aim of this study was to determine the epidemiologic features and cost of hospitalization associated with burn injuries in Iran.
Reza Rezaee, Khalil Alimohamadzadeh, Seyed-Mojtaba Hosseini   +2 more
doaj   +1 more source