Results 71 to 80 of about 254,400 (263)

Counting the costs of crime in Australia: a 2011 estimate [PDF]

, 2014
This report estimates the costs of crime for the calendar year 2011. Executive summary This report seeks to estimate how much crime costs the Australian economy by calculating the number of crimes that come to the attention of the authorities and ...
Josh Sweeney, Russell G. Smith, Georgina Fuller, Penny Jorna   +3 more
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Costs of acute otitis media in children in a city of the Colombian Caribbean coast

Biomédica: revista del Instituto Nacional de Salud, 2019
Introduction: Acute otitis media is the main cause of consultation, antibiotic use, and ambulatory surgery in developed countries; besides, it is associated with an important economic burden.
Wilfrido Coronell-Rodríguez, Cindy Arteta-Acosta, Nelson Alvis-Zakzuk, Nelson Alvis-Guzmán   +3 more
doaj   +1 more source

Costs of illness due to cholera, costs of immunization and cost-effectiveness of an oral cholera mass vaccination campaign in Zanzibar [PDF]

, 2012
BACKGROUND: The World Health Organization (WHO) recommends oral cholera vaccines (OCVs) as a supplementary tool to conventional prevention of cholera. Dukoral, a killed whole-cell two-dose OCV, was used in a mass vaccination campaign in 2009 in Zanzibar.
Claire-Lise Chaignat, Duintjer Tebbens Radboud J., Rita Reyburn, Weiss Mitchell G., Schaetti, C., Radboud J Duintjer Tebbens, Weiss, M. G., Rita Reyburn (130140), Khatib, A. M., Reyburn, R., Ahmed M. Khatib (130136), Mitchell G Weiss, Hutubessy Raymond, Schaetti Christian, Ahmed M Khatib, Claire-Lise Chaignat (127845), Raymond Hutubessy (130149), Ali, S. M., Khatib Ahmed M., Mitchell G. Weiss (130129), Chaignat Claire-Lise, Ali Said M., Hutubessy, R., Reyburn Rita, Christian Schaetti (130127), Chaignat, C. L., Raymond Hutubessy, Christian Schaetti, Said M Ali, Duintjer, Tebbens, Said M. Ali (130132), Radboud J. Duintjer Tebbens (130144)   +31 more
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Estimativa de custos diretos do Programa Municipal de Controle da Dengue de Goiânia-GO

Epidemiologia e Serviços de Saúde
OBJETIVO: estimar os custos do Programa Municipal de Controle da Dengue de Goiânia-GO, Brasil. MÉTODOS: estudo de custo de programa considerando períodos epidêmico (outubro/2009-abril/2010) e endêmico (maio-setembro/2010) de transmissão da doença, na ...
Sandra Maria dos Santos, Flúvia Amorim, Izaías de Araújo Ferreira, Giovanini Evelim Coelho, Alexander Itria, João Bosco Siqueira Junior, Cristiana Maria Toscano   +6 more
doaj   +1 more source

Best practice in estimating the costs of alcohol – Recommendations for future studies [PDF]

, 2010
This report aims to summarize best practice in estimating the attributable and avoidable costs of alcohol, and to make recommendations for making such estimates in future studies.
Baumberg Geiger, Ben
core  

Pre-operative optimisation employing dopexamine or adrenaline for patients undergoing major elective surgery: a cost-effectiveness analysis [PDF]

, 2002
<b>Objective</b>: To compare the cost and cost-effectiveness of a policy of pre-operative optimisation of oxygen delivery (using either adrenaline or dopexamine) to reduce the risk associated with major elective surgery, in high-risk patients.
Sculpher, M.J., Fenwick, E., Claxton, K., Wilson, J.   +3 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source