Results 91 to 100 of about 1,031,881 (358)

Costs of acute otitis media in children in a city of the Colombian Caribbean coast

Biomédica: revista del Instituto Nacional de Salud, 2019
Introduction: Acute otitis media is the main cause of consultation, antibiotic use, and ambulatory surgery in developed countries; besides, it is associated with an important economic burden.
Wilfrido Coronell-Rodríguez, Cindy Arteta-Acosta, Nelson Alvis-Zakzuk, Nelson Alvis-Guzmán   +3 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Projected Lifetime Healthcare Costs Associated with HIV Infection. [PDF]

, 2015
OBJECTIVE: Estimates of healthcare costs associated with HIV infection would provide valuable insight for evaluating the cost-effectiveness of possible prevention interventions.
Smith, CJ, Ruth Simmons (558172), Alec Miners, Colette J. Smith (37370), Lodwick, Rebecca K, Phillips, Andrew N, Lundgren, JD, Delpech, V, Valerie Delpech, Nakagawa, Fumiyo, Valentina Cambiano, Lundgren, Jens D., Rebecca K. Lodwick (701587), Miners Alec, Smith, Colette J., Cambiano, Valentina, Lodwick, Rebecca K., Jens D Lundgren, Lundgren, Jens D, Alec Miners (146534), Jens D. Lundgren (195772), Delpech Valerie, Ruth Simmons, Fumiyo Nakagawa (282422), Phillips, AN, Colette J Smith, Valentina Cambiano (146513), Rebecca K Lodwick, Delpech, Valerie, Andrew N Phillips, Cambiano, V, Fumiyo Nakagawa, Nakagawa Fumiyo, Simmons Ruth, Phillips Andrew N., Cambiano Valentina, Miners, Alec, Smith, Colette J, Miners, A, Andrew N. Phillips (146556), Smith Colette J., Valerie Delpech (728346), Lundgren Jens D., Lodwick, RK, Nakagawa, F, Simmons, R, Phillips, Andrew N., Lodwick Rebecca K., Simmons, Ruth   +48 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Estimativa de custos diretos do Programa Municipal de Controle da Dengue de Goiânia-GO

Epidemiologia e Serviços de Saúde
OBJETIVO: estimar os custos do Programa Municipal de Controle da Dengue de Goiânia-GO, Brasil. MÉTODOS: estudo de custo de programa considerando períodos epidêmico (outubro/2009-abril/2010) e endêmico (maio-setembro/2010) de transmissão da doença, na ...
Sandra Maria dos Santos, Flúvia Amorim, Izaías de Araújo Ferreira, Giovanini Evelim Coelho, Alexander Itria, João Bosco Siqueira Junior, Cristiana Maria Toscano   +6 more
doaj   +1 more source

Attributable healthcare utilization and cost of pneumonia due to drug-resistant streptococcus pneumonia: a cost analysis

Antimicrobial Resistance and Infection Control, 2014
The burden of disease due to S. pneumoniae (pneumococcus), particularly pneumonia, remains high despite the widespread use of vaccines. Drug resistant strains complicate clinical treatment and may increase costs.
Courtney Reynolds, J. Finkelstein, J. Finkelstein, G. Ray, M. Moore, Susan S. Huang   +5 more
semanticscholar   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Costs of publicly provided maternity services in Rosario, Argentina [PDF]

, 2003
This material is posted here with permission of the publishers, Instituto Nacional de Salud Pública. Internal or personal use of this material is permitted.
Borghi, Josephine, Belizan, María, Bastus, Silvia, Fox-Rushby, Julia, Fox-Rushby, J, Belizan, M, Carroli, Guillermo, Borghi, J, Hutton, Guy, Bastus, S, Carroli, G, Hutton, G   +11 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Endogenous Cost-Effectiveness Analysis in Health Care Technology Adoption [PDF]

Increased health care spending has been argued to be largely due to technological change. Cost-effectiveness analysis is the main tool used by private and public third-party payers to prioritize adoption of the new technologies responsible for this ...
Tomas Philipson, Anupam Jena
core