Results 91 to 100 of about 824,262 (318)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

A cost analysis of medicine donation programs to Tanzania’s neglected tropical diseases control program [PDF]

open access: yes, 2019
Masters of Public Health - see Magister Public HealthOverreliance on donor supported health programs has crippled many African countries and there is inadequate long-term planning on the future sustainability of health systems.
Rassa, Adam Omary
core  

Lack of cost analysis [PDF]

open access: yesThe Annals of The Royal College of Surgeons of England, 2010
Although this study highlights improvements in speed of treatment delivery, the suggested benefits of cost-reduction had no costing data at all. There were no comments on additional costs, such as time to review referral letters, send out Boston questionnaires and book them into the one-stop clinic. I assume that the clinical assessment of the patients
openaire   +2 more sources

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

The Full Cost of Intercity Highway Transportation [PDF]

open access: yes
In this paper we review the theoretical and empirical literature on the cost structure of the provision of intercity highway transportation and specify and estimate our own cost functions .
David Gillen, David Levinson
core  

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Cost-effectiveness in clinical trials : using multiple imputation to deal with incomplete cost data [PDF]

open access: yes, 2007
Background: Cost-effectiveness has become an important outcome in many clinical trials and has resulted in the collection of resource use data and the calculation of costs for individual patients.
Burton, Andrea   +4 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Best practice in estimating the costs of alcohol – Recommendations for future studies [PDF]

open access: yes, 2010
This report aims to summarize best practice in estimating the attributable and avoidable costs of alcohol, and to make recommendations for making such estimates in future studies.
Baumberg Geiger, Ben
core  

Cost data for individual patients included in clinical studies: no amount of statistical analysis can compensate for inadequate costing methods

open access: yes, 2002
This work examines the quality of the cost methods used to derive patient level costs in 45 economic evaluations conducted alongside randomised controlled trials.
Roberts, Jennifer A   +9 more
core   +1 more source

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