Results 91 to 100 of about 84,630 (262)

The electrogenic Na/HCO3 cotransporter

Kidney International, 1989
Cet article de synthese fait le point sur les systemes de transport du bicarbonate dans les cellules animales; (epithelium du rein et de la cornee et dans les cellules non epitheliales; cellules musculaires et nerveuses). Description des echangeurs Cl-HCO 3 dependants et independants du sodium. Sensibilite aux inhibiteurs. Stœchiometrie.
Boron, Walter F., Boulpaep, Emile L.
openaire   +2 more sources

Shorter juvenile telomere length is associated with higher survival to spawning in migratory Atlantic salmon [PDF]

, 2017
The risk of mortality associated with a long-distance migration will depend on an animal's physiological state, as well as the prevailing ecological conditions.
Armstrong, John D., Boner, Winnie, Mckelvey, Simon, McLennan, Darryl, Metcalfe, Neil B., Monaghan, Pat, Stewart, David C.   +6 more
core   +1 more source

Embryonic cerebrospinal fluid pressure in fetal mice in utero: External factors pressurize the intraventricular space

Developmental Dynamics, EarlyView.
Abstract Background Previous experiments inducing leakage of embryonic cerebrospinal fluid (CSF) suggest the necessity of intraventricular CSF pressure (PCSF) for brain morphogenesis. Nevertheless, how embryonic PCSF occurs is unclear, especially in utero. Results Using a Landis water manometer, we measured PCSF in fetal mice isolated from the amniotic
Koichiro Tsujikawa, Reina Muramatsu, Takaki Miyata   +2 more
wiley   +1 more source

Obesity Treatments to Improve Type 1 Diabetes (OTID): a randomized controlled trial of the combination of glucagon-like peptide 1 analogues and sodium-glucose cotransporter 2 inhibitors—protocol for Obesity Treatments to Improve Type 1 Diabetes (the OTID trial)

Trials
Background The guidelines of the American Diabetes Association and European Association for the Study of Diabetes suggest that patients with obesity type 2 diabetics and chronic kidney disease need either glucagon-like peptide 1 receptor analogues or ...
Ebaa Al-Ozairi, Kavita Narula, Alexander D. Miras, Etab Taghadom, Abeer El Samad, Jumana Al Kandari, Anas Alyosef, Anant Mashankar, Werd Al-Najim, Carel W. le Roux   +9 more
doaj   +1 more source

Effect of Sodium-Glucose Cotransporter Type 2 Inhibitors on The Development and Course of Atrial Fibrillation

Архивъ внутренней медицины
Atrial fibrillation is one of the most common heart rhythm disorders associated with an increased risk of stroke, cardiovascular mortality and hospitalizations.
D. A. Ishmaev, M. S. Vasileva, D. V. Duplyakov   +2 more
doaj   +1 more source

Sodium–glucose cotransporters: Functional properties and pharmaceutical potential

Journal of Diabetes Investigation, 2020
Glucose is the most abundant monosaccharide, and an essential source of energy for most living cells. Glucose transport across the cell membrane is mediated by two types of transporters: facilitative glucose transporters (gene name: solute carrier 2A ...
Ryuhei Sano, Yuichi Shinozaki, Takeshi Ohta   +2 more
doaj   +1 more source

Effect of ovariectomy on the progression of chronic kidney disease-mineral bone disorder (CKD-MBD) in female Cy/+ rats [PDF]

, 2019
Male Cy/+ rats have shown a relatively consistent pattern of progressive kidney disease development that displays multiple key features of late stage chronic kidney disease-mineral bone disorder (CKD-MBD), specifically the development of cortical bone ...
Allen, Matthew R., Chen, Neal X., Hill Gallant, Kathleen M., Lachcik, Pamela J., Metzger, Corinne E., Moe, Sharon M., Swallow, Elizabeth A., Vorland, Colby J.   +7 more
core   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Perioperative euglycemic DKA: The YIN and YANG of sodium-glucose cotransporter 2 inhibitors

Journal of Anaesthesiology Clinical Pharmacology
Sodium-glucose cotransporter 2 inhibitors are gaining widespread acceptance in managing diabetic patients due to their favorable cardiac and renal protective effects.
Shilpushp Bhosale, Akash Golani, Malini Premkumar Joshi, Atul Prabhakar Kulkarni   +3 more
doaj   +1 more source

Long‐term efficacy of the sodium–glucose cotransporter 2 inhibitor, ipragliflozin, in a case of type A insulin resistance syndrome

Journal of Diabetes Investigation, 2020
Type A insulin resistance (IR) syndrome is a severe IR form caused by insulin receptor (INSR) gene defects. Antidiabetic drugs, including high‐dose insulin and insulin‐sensitizing agents, often fail to control associated hyperglycemia.
Shuichi Nagashima, Tetsuji Wakabayashi, Naoko Saito, Manabu Takahashi, Kenta Okada, Ken Ebihara, Shun Ishibashi   +6 more
doaj   +1 more source