Results 111 to 120 of about 62,786 (347)
Сучасні медичні технологіїThe number of patients with chronic heart failure syndrome is steadily increasing worldwide and Ukraine is not an exception. About 50 % of patients with heart failure have preserved ejection fraction of left ventricle.
M. Yu. Kolesnyk, Ya. Yu. Maistrovych
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Research progress on Na+ ⁃ K+ ⁃ 2Cl- cotransporter 1 and its relationship to nervous system diseases
Chinese Journal of Contemporary Neurology and Neurosurgery, 2021 Na+ ⁃ K+ ⁃ 2Cl- cotransporter 1 (NKCC1) which plays an important role in the dynamic balance of Cl- ions, is one of the cation⁃chloride cotransporter. It is a membrane protein that transferred the mediates Na+ , K+ and Cl- .
FU Xu⁃yang +3 more
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Cotransport of water by the Na+-K+-2Cl−cotransporter NKCC1 in mammalian epithelial cells
The Journal of Physiology, 2010 Water transport by the Na+-K+-2Cl(-) cotransporter (NKCC1) was studied in confluent cultures of pigmented epithelial (PE) cells from the ciliary body of the fetal human eye. Interdependence among water, Na+ and Cl(-) fluxes mediated by NKCC1 was inferred from changes in cell water volume, monitored by intracellular self-quenching of the fluorescent dye
Hamann, Steffen +3 more
openaire +5 more sources
Biomarkers in heart failure: Traditional and emerging indicators for prognosis
ESC Heart Failure, EarlyView.
Arnold Péter Ráduly +4 more
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ESC Heart Failure, EarlyView.Abstract Background Sodium glucose cotransporter 2 inhibitors (SGLT2i) represent one of the four pillars of heart failure (HF) pharmacological therapy. Objective The study aims to clarify SGLT2i antiarrhythmic effect on patients with HF with reduced ejection fraction (HFrEF) in terms of atrial and ventricular arrhythmias (AAs and VAs) reduction ...
Marco Valerio Mariani +17 more
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Journal of Diabetes Investigation, 2020 We report the identification of a mutation in the solute carrier family 5 member 2 (SLC5A2) gene, which encodes sodium–glucose cotransporter 2, in a family with familial renal glucosuria.
Kentaro Sada +8 more
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Sodium glucose cotransporter SGLT1 as a therapeutic target in diabetes mellitus
Expert opinion on therapeutic targets, 2016 Introduction: Glycemic control is important in diabetes mellitus to minimize the progression of the disease and the risk of potentially devastating complications.
Pan-ai Song +3 more
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ESC Heart Failure, EarlyView.Non‐scaled Venn diagram of iron deficiency (ID) according to various definitions and associated outcomes. The prevalence of iron deficiency was high, irrespective of the definition applied. ID defined by TSAT <20% or serum iron <13 μmol/L, rather than the guideline definition, was associated with worse outcomes.
Xinqing Li +7 more
wiley +1 more source
A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo
Biology Open, 2012 Summary Mutations in WNK1 and WNK4 kinase genes have been shown to cause a human hereditary hypertensive disease, pseudohypoaldosteronism type II (PHAII).
Katsuyuki Oi +7 more
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Energy Balance After Sodium–Glucose Cotransporter 2 Inhibition
Diabetes Care, 2015 OBJECTIVE Sodium–glucose cotransporter 2 (SGLT2) inhibitors cause substantially less weight loss than expected from the energy excreted via glycosuria. Our aim was to analyze this phenomenon quantitatively. RESEARCH DESIGN AND METHODS Eighty-six patients
G. Ferrannini +5 more
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