Results 111 to 120 of about 95,583 (387)
Abstract Aims Heart failure with preserved ejection fraction (HFpEF) continues to be an increasingly common health problem associated with a high mortality rate. Elevated levels of Growth differentiation factor‐15 (GDF15) and N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) are reportedly associated with poor clinical outcomes in a broad range of ...
Yoichiro Otaki+11 more
wiley +1 more source
Atrial fibrillation is one of the most common heart rhythm disorders associated with an increased risk of stroke, cardiovascular mortality and hospitalizations.
D. A. Ishmaev+2 more
doaj +1 more source
Sodium–glucose cotransporters: Functional properties and pharmaceutical potential
Glucose is the most abundant monosaccharide, and an essential source of energy for most living cells. Glucose transport across the cell membrane is mediated by two types of transporters: facilitative glucose transporters (gene name: solute carrier 2A ...
Ryuhei Sano+2 more
doaj +1 more source
Expression of the Na/Pi-cotransporter Type IIb in Sf9 Cells: Functional Characterization and Purification [PDF]
In mammals the type IIb Na/Pi-cotransporter is expressed in various tissues such as intestine, brain, lung and testis. The type IIb cotransporter shows 51% homology with the renal type IIa Na/Pi-cotransporter, for which a detailed model of the secondary ...
Biber, J., Murer, H., Radanovic, T.
core
Signaling pathways involved in renal oxidative injury: role of the vasoactive peptides and the renal dopaminergic system [PDF]
The physiological hydroelectrolytic balance and the redox steady state in the kidney are accomplished by an intricate interaction between signals from extrarenal and intrarenal sources and between antinatriuretic and natriuretic factors.
Choi, Marcelo Roberto+6 more
core +3 more sources
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia+2 more
wiley +1 more source
AUP1 Regulates the Endoplasmic Reticulum-Associated Degradation and Polyubiquitination of NKCC2
Inactivating mutations of kidney Na-K-2Cl cotransporter NKCC2 lead to antenatal Bartter syndrome (BS) type 1, a life-threatening salt-losing tubulopathy.
Nadia Frachon+5 more
doaj +1 more source
A 70‐year‐old woman with type 2 diabetes was admitted to Gifu University Hospital, Gifu, Japan, because of ketosis. She was diagnosed with type 2 diabetes at age 49 years and started insulin therapy at age 57 years, which restored glycemic control ...
Megumi Yasuda+7 more
doaj +1 more source
Regulation of renal Na-HCO3 cotransporter: III. Presence and modulation by glucocorticoids in primary cultures of the proximal tubule [PDF]
Regulation of renal Na-HCO3 cotransporter: III. Presence and modulation by glucocorticoids in primary cultures of the proximal tubule. We looked for the presence of the Na-HCO3 cotransporter in primary cultures of the proximal tubule and examined the ...
Arruda, Jose A.L.+3 more
core +1 more source