Results 121 to 130 of about 84,630 (262)

Physiology of renal glucose handling via SGLT1, SGLT2 and GLUT2. [PDF]

, 2018
The concentration of glucose in plasma is held within narrow limits (4-10 mmol/l), primarily to ensure fuel supply to the brain. Kidneys play a role in glucose homeostasis in the body by ensuring that glucose is not lost in the urine.
Ghezzi, Chiara, Loo, Donald DF, Wright, Ernest M   +2 more
core  

Regulation of the Na⁺‐K⁺‐2Cl⁻ cotransporter by cGMP/cGMP‐dependent protein kinase I after furosemide administration [PDF]

, 2015
Franziska Limmer, Elisabeth Schinner, Hayo Castrop, Helga Vitzthum, Franz Hofmann, Jens Schlossmann   +5 more
openalex   +1 more source

GMP Compliant Synthesis of [¹⁸F]Canagliflozin, a Novel PET Tracer for the Sodium–Glucose Cotransporter 2

, 2021
Sjoukje van der Hoek, Inês F. Antunes, Khaled Attia, Olivier Jacquet, André Heeres, Marian Bulthuis, Rolf Zijlma, Hendrikus H. Boersma, Harry van Goor, Ton J. Visser, Hiddo J.L. Heerspink, Philip H. Elsinga, Jasper Stevens   +12 more
openalex   +1 more source

Room F, 10/16/2000 9: 00 AM - 11: 00 AM (PS) Effect of Sodium Pentobarbital on the Kinetics of the Sodium/ Bicarbonate Cotransporter in Astrocytes  [PDF]

, 2000
Ronald L. Morgan, Rona G. Giffard
openalex   +1 more source

Early administration of dapagliflozin preserves pancreatic β‐cell mass through a legacy effect in a mouse model of type 2 diabetes

Journal of Diabetes Investigation, 2019
Aims/Introduction The preservation of pancreatic β‐cell mass is an essential factor in the onset and development of type 2 diabetes mellitus. Recently, sodium–glucose cotransporter 2 inhibitors have been launched as antihyperglycemic agents, and their ...
Ayumi Kanno, Shun‐ichiro Asahara, Mao Kawamura, Ayuko Furubayashi, Shoko Tsuchiya, Emi Suzuki, Tomoko Takai, Maki Koyanagi‐Kimura, Tomokazu Matsuda, Yuko Okada, Wataru Ogawa, Yoshiaki Kido   +11 more
doaj   +1 more source

Cardiovascular effects of sodium glucose cotransporter 2 inhibitors

Diabetes, Metabolic Syndrome and Obesity, 2018
Tricia Santos Cavaiola, Jeremy Pettus Division of Endocrinology and Metabolism, University of California San Diego, San Diego, CA, USA Abstract: As the first cardiovascular (CV) outcome trial of a glucose-lowering agent to demonstrate a reduction in the ...
Santos Cavaiola T, Pettus J
doaj  

Identification of phytoconstituents from Houttuynia cordata Thunb. as dipeptidyl peptidase-IV and sodium glucose cotransporter 2 inhibitors guided by molecular docking

Phytomedicine Plus
Purpose: Houttuynia cordata Thunb. is an edible medicinal herb belonging to the Saururaceae family. Although the effects of the plant extracts on several diabetic-related parameters have been documented in the past, there is no documentation of the ...
Careen Liza Pakyntein, Daiahun Thabah, Anita Kumari Rai, Donkupar Syiem   +3 more
doaj   +1 more source

Contribution of the sympathetic nervous system to the pathogenesis of salt-sensitive hypertension [PDF]

, 2016
Dysregulation of the sodium-chloride cotransporter (NCC) is believed to significantly impact blood pressure. Recent studies have implicated overactivity of the sympathetic nervous system as a mechanism driving renal NCC dysregulation to evoke the ...
Pazzol, Michael Lee
core   +1 more source

A mutation in the Na‐K‐2Cl cotransporter‐1 leads to changes in cellular metabolism

, 2020
Salma Omer, Rainelli Koumangoye, Eric Delpire   +2 more
openalex   +2 more sources

Efficacy of Sodium-Glucose Cotransporter 2 Inhibitors on Outcomes After Catheter Ablation for Atrial Fibrillation

, 2022
Hideyuki Kishima, Takanao Mine, Eiji Fukuhara, Ryo Kitagaki, Masanori Asakura, Masaharu Ishihara   +5 more
openalex   +1 more source