European Journal of Heart Failure, EarlyView.Myocardial ketone body oxidation contributes to empagliflozin‐induced improvements in cardiac contractility. Abstract Aims Sodium–glucose cotransporter 2 inhibitors (SGLT2i) improve cardiac performance and clinical outcomes in patients with heart failure, yet mechanisms underlying these beneficial effects remain incompletely understood.
Suzanne Nathalie Voorrips +11 more
wiley +1 more source
Shedding light on the effects of sodium-glucose cotransporter 2 inhibitors in the early stages of heart failure. [PDF]
World J CardiolFalco L, Di Lorenzo E, Masarone D.
europepmc +1 more source
Isolation and Localization of Type IIb Na/Pi Cotransporter in the Developing Rat Lung [PDF]
, 2000 Mitsuyoshi Hashimoto +7 more
openalex +1 more source
European Journal of Heart Failure, EarlyView.Linking guideline‐directed medical therapy (GDMT) implementation and appropriate polypharmacy management in heart failure (HF). Polypharmacy can represent a barrier to the proper implementation of life‐prolonging GDMT for HF. A reasonable balance between the optimization of GDMT and avoiding inappropriate polypharmacy is mandatory in the contemporary ...
Davide Stolfo +27 more
wiley +1 more source
Molecular Determinants of pH Sensitivity of the Type IIa Na/Pi Cotransporter [PDF]
, 2000 Carmen de la Horra +5 more
openalex +1 more source
Cardioprotective effects of semaglutide on isolated human ventricular myocardium
European Journal of Heart Failure, EarlyView.Semaglutide reduces late sodium current (INa) and diastolic calcium (Ca) sparks in human cardiomyocytes from aortic stenosis (AS) and end‐stage heart failure with reduced ejection fraction (HFrEF) patients, thereby increasing Ca transients. Improved Ca storage may underly the enhanced contractility of human cardiomyocytes upon semaglutide.
Thomas Krammer +16 more
wiley +1 more source
The World Congress of Insulin Resistance, Diabetes and Cardiovascular Disease (WCIRDC)
, 2023 Journal of Diabetes, Volume 15, Issue 1, Page 4-6, January 2023.
Zachary T. Bloomgarden
wiley +1 more source
Optimizing SGLT2 inhibitor and GLP-1 RA prescribing in high-risk patients with diabetes: a Department of Veterans Affairs quality improvement intervention. [PDF]
BMC Prim CareYun S +5 more
europepmc +1 more source
Lower extremity lymphatic flow is associated with diuretic response in acute heart failure
European Journal of Heart Failure, EarlyView.Lower extremity lymphatic flow and diuretic response in acute heart failure (AHF). IV, intravenous. (Created in BioRender) Abstract AimsThe dysfunctional lymphatic system appears to play an important role in the development and progression of congestion in heart failure. We hypothesized that in acute heart failure (AHF), diuretic efficacy is associated
Barbara Ponikowska +6 more
wiley +1 more source
SGLT2 inhibitor use and renal outcomes in low-risk population with diabetes mellitus and normal or low body mass index. [PDF]
BMJ Open Diabetes Res CareLee YS +6 more
europepmc +1 more source