Results 231 to 240 of about 84,630 (262)

Na+–sulfate cotransporter SLC13A1

Pflügers Archiv - European Journal of Physiology, 2013
Sulfate is essential for normal physiology. The kidney plays a major role in sulfate homeostasis. Sulfate is freely filtered and strongly reabsorbed in the proximal tubule. The apical membrane Na(+)-sulfate cotransporter NaS1 (SLC13A1) mediates sulfate (re)absorption across renal proximal tubule and small intestinal epithelia.
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Analyzing an electrogenic cotransporter

The Journal of Membrane Biology, 1993
A model for the sodium-dependent accumulation of glutamate by synaptosomes has been presented which fits the data of Wheeler and his coworkers and supports their hypothesis of an electrogenic cotransporter. Since their hypothesis was based on experimental data on the operation of the cotransporter on the outer membrane, the model was expanded to ...
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MOLECULAR ASPECTS OF SUGAR:ION COTRANSPORT

Annual Review of Biochemistry, 1986
INTRODUCTION .... . . . . . . . .. . COTRANSPORTERS .... . . .... .. . COTRANSPORT IN THEORy . . . . . ....... . . . . ... . . . . . . . . . . . ....... . . . . . . . .. . .... . . . .... . COTRANSPORT IN PRACTICE . . . . . . . . . . . . . ....... .. . . . . . . . . . .. ... . . .. .. . . . . ... .. . . . . . . .. ...... .
J K, Wright, R, Seckler, P, Overath
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Sodium-Potassium-Chloride Cotransport

Physiological Reviews, 2000
Obligatory, coupled cotransport of Na+, K+, and Cl−by cell membranes has been reported in nearly every animal cell type. This review examines the current status of our knowledge about this ion transport mechanism. Two isoforms of the Na+-K+-Cl−cotransporter (NKCC) protein (∼120–130 kDa, unglycosylated) are currently known.
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The Na-K-Cl Cotransporters

Journal of Bioenergetics and Biomembranes, 1998
The Na-K-Cl cotransporters are a class of membrane proteins that transport Na, K, and Cl ions into and out of a wide variety of epithelial and nonepithelial cells. The transport process mediated by Na-K-Cl cotransporters is characterized by electroneutrality (almost always with stoichiometry of 1Na:1K:2Cl) and inhibition by the "loop" diuretics ...
M, Haas, B, Forbush
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Random-walk model of cotransport

Physical Review E, 2020
We present a statistical mechanical model to describe the dynamics of an arbitrary cotransport system. Our starting point was the alternating access mechanism, which suggests the existence of six states for the cotransport cycle. Then we determined the 14 transition probabilities between these states, including a leak pathway, and used them to write a ...
Yan B. Barreto, Béla Suki, Adriano M. Alencar   +2 more
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Molecular Mechanisms of NaCl Cotransport

Annual Review of Physiology, 1996
Electroneutral Na-(K)-Cl cotransporters are present in most cell types, where they play an important role in both sodium-chloride absorption and secretion and cell volume regulation. Recent advances in the molecular identification of these cotransporters have provided a new level of insight into the mechanisms of sodium-chloride-coupled cotransport and
M R Kaplan, D B Mount, E Delpire, G Gamba, S C Hebert   +4 more
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The overshoot phenomenon in cotransport

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1984
Based on simplified equations, the overshoot curve experimentally observed with Na+-linked cotransport of neutral substrate (sugars or amino acids) has been simulated by computer. The approach is in principle similar to that of previous approaches (Weiss, S.D., McNamara, P.D. and Segal, S. (1981) J. Theor. Biol.
E, Heinz, A M, Weinstein
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Regulation of Na+/Glucose Cotransporters

Journal of Experimental Biology, 1997
ABSTRACT Na+/glucose cotransporters (SGLTs) are expressed in the small intestine and the proximal renal tubule, where they play a central role in the absorption of glucose and galactose from food and the reabsorption of glucose from the glomerular filtrate.
E M, Wright, J R, Hirsch, D D, Loo, G A, Zampighi   +3 more
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Renal Na⁺-glucose cotransporters

American Journal of Physiology-Renal Physiology, 2001
In humans, the kidneys filter ∼180 g of d-glucose from plasma each day, and this is normally reabsorbed in the proximal tubules. Although the mechanism of reabsorption is well understood, Na+-glucose cotransport across the brush-border membrane and facilitated diffusion across the basolateral membrane, questions remain about the identity of the genes ...
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