Results 241 to 250 of about 84,630 (262)
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The Electroneutral Cation–Chloride Cotransporters
Journal of Experimental Biology, 1998ABSTRACT Electroneutral cation–chloride cotransporters are widely expressed and perform a variety of physiological roles. A novel gene family of five members, encompassing a Na+–Cl− transporter, two Na+–K+–2Cl− transporters and two K+–Cl− cotransporters, encodes these membrane proteins; homologous genes have also been identified in a ...
D B, Mount +6 more
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[Na+/K+/2Cl- cotransport protein, Na+/Cl- cotransport protein].
Nihon rinsho. Japanese journal of clinical medicine, 1997The bumetanide-sensitive Na+/K+/2Cl- cotransporter and the thiazide-sensitive Na+/Cl- cotransporter are present in a wide variety of tissues, and appear to serve physiological cell functions such as volume control, particularly the phenomenon known as regulatory volume control, and net secretion or absorption of salt.
T, Inoue, H, Nonoguchi, K, Tomita
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Methods in enzymology, 1989
Two methods have been described for the study of cation-chloride cotransport systems. The zero-trans efflux method is designed to determine stoichiometric relationships between cotransported ions under conditions where ion exchanges cannot occur. These exchanges (e.g., Na+/Na+, K+/K+) may occur as partial or incomplete reactions of a cotransport ...
M, Haas, T J, McManus
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Two methods have been described for the study of cation-chloride cotransport systems. The zero-trans efflux method is designed to determine stoichiometric relationships between cotransported ions under conditions where ion exchanges cannot occur. These exchanges (e.g., Na+/Na+, K+/K+) may occur as partial or incomplete reactions of a cotransport ...
M, Haas, T J, McManus
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Prolactin increases mRNA encoding Na(+)-TC cotransport polypeptide and hepatic Na(+)-TC cotransport
American Journal of Physiology-Gastrointestinal and Liver Physiology, 1995We have shown that prolactin (Prl) increases the transhepatic transport of taurocholate (TC) in postpartum rats and following treatment of ovariectomized (Ovx) rats with ovine Prl (oPrl). The present studies were designed to determine if treatment of Ovx rats with oPrl (100, 300, or 600 micrograms/day, 7 days iv) 1) increases Na(+)-TC cotransport in ...
Y, Liu, T, Ganguly, J F, Hyde, M, Vore
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Sodium Glucose Cotransporter 2 Inhibitors
Medical Clinics of North America, 2015SGLT2 inhibition offers a novel mechanism to mitigate hyperglycemia in patients with diabetes and the introduction of SGLT2 has added a significant new tool to the antihyperglycemic armamentarium. At present, 2 agents are approved for use in the United States and several more are in development.
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Sodium-Sulfate/Carboxylate Cotransporters (SLC13)
2012The SLC13 gene family is comprised of five sequence related proteins that are found in animals, plants, yeast and bacteria. Proteins encoded by the SLC13 genes are divided into the following two groups of transporters with distinct anion specificities: the Na(+)-sulfate (NaS) cotransporters and the Na(+)-carboxylate (NaC) cotransporters.
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American Journal of Physiology-Cell Physiology, 1994
The Na-K-Cl cotransporters are a class of membrane proteins that transport Na, K, and Cl ions into and out of cells in an electrically neutral manner, in most cases with a stoichiometry of 1Na:1K:2Cl. Na-K-Cl cotransporters are present in a wide variety of cells and tissues, including reabsorptive and secretory epithelia, nerve and muscle cells ...
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The Na-K-Cl cotransporters are a class of membrane proteins that transport Na, K, and Cl ions into and out of cells in an electrically neutral manner, in most cases with a stoichiometry of 1Na:1K:2Cl. Na-K-Cl cotransporters are present in a wide variety of cells and tissues, including reabsorptive and secretory epithelia, nerve and muscle cells ...
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