Results 361 to 370 of about 95,583 (387)

MOLECULAR ASPECTS OF SUGAR:ION COTRANSPORT

Annual Review of Biochemistry, 1986
INTRODUCTION .... . . . . . . . .. . COTRANSPORTERS .... . . .... .. . COTRANSPORT IN THEORy . . . . . ....... . . . . ... . . . . . . . . . . . ....... . . . . . . . .. . .... . . . .... . COTRANSPORT IN PRACTICE . . . . . . . . . . . . . ....... .. . . . . . . . . . .. ... . . .. .. . . . . ... .. . . . . . . .. ...... .
Robert Seckler, Peter Overath, J. Keith Wright   +2 more
openaire   +3 more sources

Na+-K+-2Cl− Cotransporter [PDF]

, 2015
The conceptual breakthrough that the energy of the Na+ gradient generated by the Na+/K+ pump could be used as the driving force for another membrane transport protein has led to the functional and molecular identification of multiple secondary active transporters.
Eric Delpire, Kenneth B. Gagnon
openaire   +1 more source

Fournier Gangrene Associated With SodiumGlucose Cotransporter-2 Inhibitors

Annals of Internal Medicine, 2019
Fournier gangrene (FG) was named for Jean Alfred Fournier, a French dermatologist and venereologist who, in 1883, described a perineal disease of acute onset and rapid progression in previously healthy young men (1).
S. Bersoff-Matcha, C. Chamberlain, Christian Cao, C. Kortepeter, W. Chong   +4 more
semanticscholar   +1 more source

Cotransporters, WNKs and hypertension: an update

Current Opinion in Nephrology & Hypertension, 2008
Studies of inherited conditions characterized by high or low blood pressure reveal the importance of a new signalling cascade, With no Lysine kinases (WNK) --> ste20/SPS1-related proline/alanine-rich kinase (SPAK)/oxidative stress-responsive kinase-1 (OSR1) --> Cation-Chloride Cotransporters (CCC), in regulating blood pressure and in the pathogenesis ...
openaire   +2 more sources

Stochastic models of cotransport

Transport Theory and Statistical Physics, 1993
The author constructs discrete Boltzmann equations describing the reactions between any number of chemicals. By including a heat particle to balance the energy, a model is constructed for the chemistry of liquids that obeys the Arrhenius relation. It is proven that all isolated systems within this class of models converge to equilibrium. The models are
openaire   +2 more sources

Renal Na⁺-glucose cotransporters [PDF]

American Journal of Physiology-Renal Physiology, 2001
In humans, the kidneys filter ∼180 g of d-glucose from plasma each day, and this is normally reabsorbed in the proximal tubules. Although the mechanism of reabsorption is well understood, Na+-glucose cotransport across the brush-border membrane and facilitated diffusion across the basolateral membrane, questions remain about the identity of the genes ...
openaire   +2 more sources

Effect of sodium‐glucose cotransporter 2 inhibitor, empagliflozin, and α‐glucosidase inhibitor, voglibose, on hepatic steatosis in an animal model of type 2 diabetes

Journal of Cellular Biochemistry, 2018
We investigated the effects of sodium‐glucose cotransporter 2 inhibitor, empagliflozin, and α‐glucosidase inhibitor, voglibose, on hepatic steatosis in an animal model of type 2 diabetes (T2DM).
Ji‐Won Kim, Ye-Jee Lee, Y. You, M. Moon, K. Yoon, Y. Ahn, Seung-Hyun Ko   +6 more
semanticscholar   +1 more source

The Na-K-Cl cotransporters

American Journal of Physiology-Cell Physiology, 1994
The Na-K-Cl cotransporters are a class of membrane proteins that transport Na, K, and Cl ions into and out of cells in an electrically neutral manner, in most cases with a stoichiometry of 1Na:1K:2Cl. Na-K-Cl cotransporters are present in a wide variety of cells and tissues, including reabsorptive and secretory epithelia, nerve and muscle cells ...
openaire   +3 more sources

Endothelial Na-K-Cl cotransport regulation by tonicity and hormones: phosphorylation of cotransport protein

American Journal of Physiology-Cell Physiology, 1995
The Na-K-Cl cotransport system of vascular endothelial cells plays a central role in maintenance and regulation of intracellular volume. Activity of the cotransporter is modulated both by hormones and by extracellular tonicity. Vasopressin and other hormones that stimulate the endothelial cotransporter act via a Ca- and calmodulin-dependent pathway ...
Martha E O'Donnell, Dandan Sun, Anthony Martinez   +2 more
openaire   +3 more sources

Mechanisms of Cardiorenal Effects of Sodium-Glucose Cotransporter 2 Inhibitors: JACC State-of-the-Art Review.

Journal of the American College of Cardiology, 2020
Thomas A. Zelniker, E. Braunwald
semanticscholar   +1 more source