Results 31 to 40 of about 62,786 (347)
Intestinal gluconeogenesis and glucose transport according to body fuel availability in rats [PDF]
J Physiol 566 (15/07/2005) 575-86, 2007 Intestinal hexose absorption and gluconeogenesis have been studied in relation to refeeding after two different fasting phases: a long period of protein sparing during which energy expenditure is derived from lipid oxidation (phase II), and a later phase characterized by a rise in plasma corticosterone triggering protein catabolism (phase III).
arxiv +1 more source
Circulation, 2017 Background: Reduction in cardiovascular death and hospitalization for heart failure (HHF) was recently reported with the sodium-glucose cotransporter-2 inhibitor (SGLT-2i) empagliflozin in patients with type 2 diabetes mellitus who have atherosclerotic ...
M. Kosiborod +13 more
semanticscholar +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background Sodium‐glucose cotransporter 2 inhibitors improve cardiovascular outcomes in patients with diabetes with and without heart failure (HF). However, their influence on sympathetic nerve activity (SNA) remains unclear.
Takuto Hamaoka +12 more
doaj +1 more source
A Systemic Receptor Network Triggered by Human cytomegalovirus Entry [PDF]
Advances in Virology Volume 2011 (2011), Article ID 262080, 11
pages, 2010 Virus entry is a multistep process that triggers a variety of cellular pathways interconnecting into a complex network, yet the molecular complexity of this network remains largely unsolved. Here, by employing systems biology approach, we reveal a systemic virus-entry network initiated by human cytomegalovirus (HCMV), a widespread opportunistic ...
arxiv +1 more source
Diabetes, 2016 Pharmacologically induced glycosuria elicits adaptive responses in glucose homeostasis and hormone release. In type 2 diabetes (T2D), along with decrements in plasma glucose and insulin levels and increments in glucagon release, sodium–glucose ...
E. Ferrannini +8 more
semanticscholar +1 more source
Kidney International, 1996 Two non-homologous proximal tubular apical Na/Pi-cotransport systems (type I and type II) have been identified thus far by expression cloning. Subsequent studies provided evidence that the type II Na/Pi-cotransporter represents a target for the physiological and pathophysiological regulation of proximal reabsorption of phosphate.
Biber, J +7 more
openaire +3 more sources
Kidney International, 1989 The KCl cotransporter in the basolateral membrane of renal tubules may play a central role in the transcellular transport of NaCl. Because this transporter is electrically neutral, and also functions in parallel to the electrogenic Na,K-ATPase, there is an imbalance in charge which must be expressed as a cationic current across the basolateral membrane.
David G. Warnock, Jill Eveloff
openaire +3 more sources
Journal of Diabetes Investigation, 2019 Cardiorenal protective effects of sodium–glucose cotransporter 2 inhibitors are difficult to explain. From the recent works by Takagi et al. and an expert consensus report, I suggest further works on the effects of sodium–glucose cotransporter ...
Hong Kyu Lee
doaj +1 more source
Structure-function relationships in the sodium chloride cotransporter
Frontiers in Physiology, 2023 The thiazide sensitive Na+:Cl− cotransporter (NCC) is the principal via for salt reabsorption in the apical membrane of the distal convoluted tubule (DCT) in mammals and plays a fundamental role in managing blood pressure.
Erika Moreno +6 more
doaj +1 more source
International Journal of Molecular Sciences, 2019 The renin-angiotensin system (RAS) plays an important role in regulating body fluids and blood pressure. However, inappropriate activation of the RAS contributes to the pathogenesis of cardiovascular and renal diseases.
Tuba M Ansary, D. Nakano, A. Nishiyama
semanticscholar +1 more source