Results 41 to 50 of about 95,583 (387)
Active site voltage clamp fluorometry of the sodium glucose cotransporter hSGLT1. [PDF]
, 2017 In the human sodium glucose cotransporter (hSGLT1) cycle, the protein undergoes conformational changes where the sugar-binding site alternatively faces the external and internal surfaces.
Gorraitz, Edurne +4 more
core +2 more sources
Kidney International, 1989 The KCl cotransporter in the basolateral membrane of renal tubules may play a central role in the transcellular transport of NaCl. Because this transporter is electrically neutral, and also functions in parallel to the electrogenic Na,K-ATPase, there is an imbalance in charge which must be expressed as a cationic current across the basolateral membrane.
David G. Warnock, Jill Eveloff
openaire +3 more sources
Structure-function relationships in the sodium chloride cotransporter
Frontiers in Physiology, 2023 The thiazide sensitive Na+:Cl− cotransporter (NCC) is the principal via for salt reabsorption in the apical membrane of the distal convoluted tubule (DCT) in mammals and plays a fundamental role in managing blood pressure.
Erika Moreno +6 more
doaj +1 more source
Sodium-substrate cotransport in bacteria
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2001 A variety of sodium-substrate cotransport systems are known in bacteria. Sodium enters the cell down an electrochemical concentration gradient. There is obligatory coupling between the entry of the ion and the entry of substrate with a stoichiometry (in the cases studied) of 1:1.
Ping Z. Ding, T.H. Wilson
openaire +3 more sources
Journal of Diabetes Investigation, 2020 Sodium–glucose cotransporter 2 inhibitors, as well as thiazolidines, suppress nonalcoholic fatty liver disease (NAFLD); however, few comparative studies have been reported.
K. Cho +12 more
semanticscholar +1 more source
The electrogenic Na/HCO3 cotransporter
Kidney International, 1989 Cet article de synthese fait le point sur les systemes de transport du bicarbonate dans les cellules animales; (epithelium du rein et de la cornee et dans les cellules non epitheliales; cellules musculaires et nerveuses). Description des echangeurs Cl-HCO 3 dependants et independants du sodium. Sensibilite aux inhibiteurs. Stœchiometrie.
Walter F. Boron, Emile L. Boulpaep
openaire +3 more sources
Journal of Diabetes Investigation, 2020 Recent studies have shown that sodium–glucose cotransporter 2 inhibitors decrease the risk of heart failure in patients with type 2 diabetes. However, the precise mechanisms of action of these drugs are not well understood.
Mayu Tochiya +11 more
doaj +1 more source
A Cl- cotransporter selective for NH4+ over K+ in glial cells of bee retina [PDF]
, 2000 There appears to be a flux of ammonium (NH4+/NH3) from neurons to glial cells in most nervous tissues. In bee retinal glial cells, NH4+/NH3 uptake is at least partly by chloride-dependant transport of the ionic form NH4+.
Abramowitz +56 more
core +4 more sources
Cell volume regulation in the proximal tubule of rat kidney proximal tubule cell volume regulation [PDF]
, 2017 We developed a dynamic model of a rat proximal convoluted tubule cell in order to investigate cell volume regulation mechanisms in this nephron segment.
Edwards, Aurelie, Layton, Anita T.
core +1 more source
Cotransporter-mediated water transport underlying cerebrospinal fluid formation
Nature Communications, 2018 Cerebrospinal fluid (CSF) production occurs at a rate of 500 ml per day in the adult human. Conventional osmotic forces do not suffice to support such production rate and the molecular mechanisms underlying this fluid production remain elusive.
A. B. Steffensen +7 more
semanticscholar +1 more source