Results 51 to 60 of about 62,786 (347)
Advanced Science, EarlyView.New research reveals that oxytocin signaling during the early postnatal period is critical for regulating brain development and social behavior. Selectively suppressing oxytocin neurons by chemogenetic method shows that early—but not late—disruption leads to autism‐like behaviors.
Zi‐Hui Wang +10 more
wiley +1 more source
Mìžnarodnij Endokrinologìčnij Žurnal, 2021 The article presents the literature review of the possibilities of modern antidiabetic therapy in the prevention of chronic kidney disease in patients with type 2 diabetes mellitus.
V.I. Katerenchuk
doaj +1 more source
Circulation, 2014 Background— The primary objective of this mechanistic open-label, stratified clinical trial was to determine the effect of 8 weeks’ sodium glucose cotransporter 2 inhibition with empagliflozin 25 mg QD on renal hyperfiltration in subjects with type 1 ...
D. Cherney +10 more
semanticscholar +1 more source
Nature Communications, 2020 The secondary active cation–chloride cotransporters (CCCs) utilize the existing Na+ and/or K+ gradients to move Cl− into or out of cells. NKCC1 is an intensively studied member of the CCC family and plays fundamental roles in regulating trans-epithelial ...
Xiaoyong Yang, Qinzhe Wang, E. Cao
semanticscholar +1 more source
The sodium phosphate cotransporter family SLC34 [PDF]
Pfl�gers Archiv European Journal of Physiology, 2004 This review summarizes the characteristics of the solute carrier family SLC34 that is represented by the type ll Na/P(i)-cotransporters NaPi-lla (SLC34A1), NaPi-llb (SLC34A2) and NaPi-llc (SLC34A3). Other Na/P(i)-cotransporters are described within the SLC17 and SLC20 families.
Murer, H, Forster, I C, Biber, J
openaire +5 more sources
Advanced Microfluidic‐Based Wearable Electrochemical Sensors for Continuous Biochemical Monitoring
Advanced Electronic Materials, EarlyView.Microfluidic‐based wearable electrochemical sensors are transforming non‐invasive health monitoring through real‐time biochemical analysis of sweat, saliva, and interstitial fluid. This review explores advances in microfluidic design, fabrication, and sensor integration while addressing biofluid variability, material compatibility, and scalability.
Sehyun Park +5 more
wiley +1 more source
Sodium‐glucose cotransporter 1 as a sugar taste sensor in mouse tongue
Acta Physiologica, 2020 We investigated potential neuron types that code sugar information and how sodium‐glucose cotransporters (SGLTs) and T1Rs are involved.
K. Yasumatsu +5 more
semanticscholar +1 more source
SAGE Open MedicineBackground: Sodium glucose cotransporter 2 inhibitors are recommended for the treatment of heart failure due to their cardioprotective effects, despite primarily being used as antidiabetic medications. However, the comparative profile of two antidiabetic
Abhigan Babu Shrestha +13 more
doaj +1 more source
Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients.
Journal of Clinical Investigation, 2014 BACKGROUND Sodium-glucose cotransporter 2 (SGLT2) inhibitors lower glycemia by enhancing urinary glucose excretion. The physiologic response to pharmacologically induced acute or chronic glycosuria has not been investigated in human diabetes.
E. Ferrannini +7 more
semanticscholar +1 more source
Diabetes, 2016 Canagliflozin, dapagliflozin, and empagliflozin, all recently approved for treatment of type 2 diabetes, were derived from the natural product phlorizin. They reduce hyperglycemia by inhibiting glucose reuptake by sodium/glucose cotransporter (SGLT) 2 in
S. Hawley +9 more
semanticscholar +1 more source