Results 61 to 70 of about 28,882 (293)

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden   +3 more
wiley   +1 more source

Angel Groups: Developing a Regional Economic Development Strategy for Robust Seed Capital Ecosystems for Entrepreneurs [PDF]

open access: yes, 2016
The purpose of this paper is to identify the link between the success of angel organizational structures and the economic footprint within which angel groups operate; ultimately suggesting a novel approach of assisting traditional angel group structures ...
Rodriguez, Kendre Esme
core   +1 more source

Cougar Dispersal and Natal Homing in a Desert Environment

open access: yes, 2018
We present a review of cougar dispersal literature and the first evidence of natural (i.e., unmanipulated) homing behavior by a dispersing male cougar (Puma concolor) that sustained severe injuries crossing the northern Mojave Desert.
Choate, David M.   +2 more
core   +1 more source

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst   +8 more
wiley   +1 more source

Humans as Prey: Coping with Large Carnivore Attacks using a Predator-Prey Interaction Perspective

open access: yesHuman-Wildlife Interactions, 2017
The number of attacks on humans by large carnivores in North America is increasing. A better understanding the factors triggering such attacks is critical to mitigating the risk of future encounters in landscape where humans and large carnivore co-exist.
Vincenzo Penteriani   +6 more
doaj   +1 more source

Bed site selection by a subordinate predator: an example with the cougar (Puma concolor) in the Greater Yellowstone Ecosystem [PDF]

open access: yesPeerJ, 2017
As technology has improved, our ability to study cryptic animal behavior has increased. Bed site selection is one such example. Among prey species, bed site selection provides thermoregulatory benefits and mitigates predation risk, and may directly ...
Anna Kusler   +3 more
doaj   +2 more sources

Medians and Beyond: New Aggregation Techniques for Sensor Networks [PDF]

open access: yes, 2004
Wireless sensor networks offer the potential to span and monitor large geographical areas inexpensively. Sensors, however, have significant power constraint (battery life), making communication very expensive.
Agrawal, Divyakant   +3 more
core   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

open access: yesBMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan   +8 more
wiley   +1 more source

Spartan Daily, February 6, 1953 [PDF]

open access: yes, 1953
Volume 41, Issue 84https://scholarworks.sjsu.edu/spartandaily/11831/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

open access: yesBMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu   +5 more
wiley   +1 more source

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