Results 1 to 10 of about 124,281 (312)
PUMA reduces FASN ubiquitination to promote lipid accumulation and tumor progression in human clear cell renal cell carcinoma [PDF]
While the p53 upregulated modulator of apoptosis (PUMA) is traditionally recognized for promoting cell apoptosis and enhancing chemotherapy efficacy in various cancers, its role in clear cell renal cell carcinoma (ccRCC) remains unclear due to ccRCC’s ...
Qianqian Luo +8 more
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Cardioprotective effect of Ginger in a rat model of myocardial damage and its possible intervention in PERK-ATF4-CHOP-PUMA apoptotic pathway [PDF]
For today the exact mechanisms of myocardial infarction and ischemia/reperfusion injury are still not fully understood. ER stress and integrated stress response pathways are thought to play an essential role in myocardial damage. This includes activation
M. M. Mohammed +3 more
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PUMA, antiProton unstable matter annihilation
AbstractPUMA, antiProton Unstable Matter Annihilation, is a nuclear-physics experiment at CERN aiming at probing the surface properties of stable and rare isotopes by use of low-energy antiprotons. Low-energy antiprotons offer a very unique sensitivity to the neutron and proton densities at the annihilation site, i.e. in the tail of the nuclear density.
Aumann, T. +54 more
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PUMA mediated afatinib-induced apoptosis in glioma cells
Introduction Afatinib exhibits a tumor-inhibiting effect in different cancers by inducing apoptosis; however, its pro-apoptosis role in glioma cells is still not fully understood. Material and methods In the current study, two glioma cell lines (U373-MG
Rongzhong Lu +3 more
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There is a paucity of published hematological data for wild, free-ranging mountain lions (Puma concolor). We collected such information from mountain lions occurring at mid-elevations to increase available baseline information. We captured and sampled
Vernon C. Bleich +3 more
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Genomic ancestry of the American puma (Puma concolor) [PDF]
Puma concolor, a large American cat species, occupies the most extensive range of any New World terrestrial mammal, spanning 110 degrees of latitude from the Canadian Yukon to the Straits of Magellan. Until the recent Holocene, pumas coexisted with a diverse array of carnivores including the American lion (Panthera atrox), the North American cheetah ...
Culver, Melanie +3 more
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Puma (Puma concolor) epididymal sperm morphometry
The Andean puma (Puma concolor) has not been widely studied, particularly in reference to its semen characteristics. The aim of the present study was to define the morphometry of puma sperm heads and classify their subpopulations by cluster analysis. Samples were recovered postmortem from two epididymides from one animal and prepared for morphological ...
Hernán Cucho +5 more
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Pyrrolyl Squaraines–Fifty Golden Years
Pyrrolyl squaraines, both dyes and polymers, were first reported in 1965 and since then a fascinating body of work has been produced investigating the chemistry of these interesting molecules.
Daniel E. Lynch
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Comments on Lynch. Pyrrolyl Squaraines—Fifty Golden Years. Metals 2015, 5, 1349–1370
In addition to the papers referenced in the main article [1]; [...]
Daniel E. Lynch
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Diarrhea is one of the most commonly reported adverse effect of hemotherapy and targeted cancer therapies, such as tyrosine kinase inhibitors (TKI), which often significantly impact patient quality of life, morbidity, and mortality. Neratinib is an oral,
Taras Lysyy +4 more
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