Results 21 to 30 of about 28,540 (263)

The p53-target gene puma drives neutrophil-mediated protection against lethal bacterial sepsis. [PDF]

PLoS Pathogens, 2010
Disruption of p53/Puma-mediated apoptosis protects against lethality due to DNA damage. Here we demonstrate the unexpected requirement of the pro-apoptotic p53-target gene Puma to mount a successful innate immune response to bacterial sepsis.
Sean P Garrison, Justin A Thornton, Hans Häcker, Richard Webby, Jerold E Rehg, Evan Parganas, Gerard P Zambetti, Elaine I Tuomanen   +7 more
doaj   +1 more source

Survival and Mortality of Pumas (Puma concolor) in a Fragmented, Urbanizing Landscape [PDF]

Proceedings of the Vertebrate Pest Conference, 2015
Wide-ranging large carnivores pose myriad challenges for conservation, especially in highly fragmented landscapes. Over a 13-year period, we combined monitoring of radio collared pumas (Puma concolor) with complementary multi-generational genetic analyses to inform puma conservation in southern California, USA.
Vickers, T. Winston, Sanchez, Jessica N., Johnson, Christine K., Morrison, Scott A., Botta, Randy, Smith, Trish, Cohen, Brian S., Huber, Patrick, Ernest, Holly B., Boyce, Walter M.   +9 more
openaire   +8 more sources

Chronic inflammation evoked by pathogenic stimulus during carcinogenesis

4 open, 2019
A pathogenic (biological or chemical) stimulus is the earliest information received by a cell that can result in the disruption of homeostasis with consequent development of disease.
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source

Presencia suburbana de Puma concolor (Carnivora: Felidae) en el cantón de San Ramón, Alajuela, Costa Rica

Mammalogy Notes, 2017
El 19 de marzo de 2016 a las 14h50 observamos un Puma en un parche de bosque pequeño (5,2 ha) en el distrito de Santiago, San Ramón, Provincia de Alajuela, Costa Rica (10,057109° N, -84,492416° W; Figura 2).
Brayan Heiner Morera-Chacón, Yaina Ruiz-Chaves   +1 more
doaj   +1 more source

PUMA, antiProton unstable matter annihilation

The European Physical Journal A, 2022
AbstractPUMA, antiProton Unstable Matter Annihilation, is a nuclear-physics experiment at CERN aiming at probing the surface properties of stable and rare isotopes by use of low-energy antiprotons. Low-energy antiprotons offer a very unique sensitivity to the neutron and proton densities at the annihilation site, i.e. in the tail of the nuclear density.
Aumann, T., Bartmann, W., Boine-Frankenheim, O., Bouvard, A., Broche, A., Butin, F., Calvet, D., Carbonell, J., Chiggiato, P., De Gersem, H., De Oliveira, R., Dobers, T., Ehm, F., Somoza, J. Ferreira, Fischer, J., Fraser, M., Friedrich, E., Frotscher, A., Gomez-Ramos, M., Grenard, J-L., Hobl, A., Hupin, G., Husson, A., Indelicato, P., Johnston, K., Klink, C., Kubota, Y., Lazauskas, R., Malbrunot-Ettenauer, S., Marsic, N., Mueller, W.FO., Naimi, S., Nakatsuka, N., Necca, R., Neidherr, D., Neyens, G., Obertelli, A., Ono, Y., Pasinelli, S., Paul, N., Pollacco, E.C., Rossi, D., Scheit, H., Schlaich, M., Schmidt, A., Schweikhard, L., Seki, R., Sels, S., Siesling, E., Uesaka, T., Vilen, M., Wada, M., Wienholtz, F., Wycech, S., Zacarias, S.   +54 more
openaire   +2 more sources

Establishing essential oil stewardship through the case of rosemary and thyme oils against Staphylococcus aureus

Frontiers in Microbiology
Essential oils (EOs) have long been studied for their antimicrobial properties, yet most investigations rely on simplistic models, limited strain panels, and anecdotal interpretations—failing to meet the standards expected of modern anti-infective agents.
Malwina Brożyna, Zuzanna Stępnicka, Zuzanna Stępnicka, Katarzyna Kapczyńska, Bartłomiej Dudek, Adam Matkowski, Adam Junka   +6 more
doaj   +1 more source

HER2 phosphorylates and destabilizes pro-apoptotic PUMA, leading to antagonized apoptosis in cancer cells.

PLoS ONE, 2013
HER2 is overexpressed in 15-20% of breast cancers. HER2 overexpression is known to reduce apoptosis but the underlying mechanisms for this association remain unclear.
Richard L Carpenter, Woody Han, Ivy Paw, Hui-Wen Lo   +3 more
doaj   +1 more source

Papillary architecture of the lingual surface in the puma (Puma concolor)

Anatomia, Histologia, Embryologia, 2017
SummaryThis research presents the first anatomical description of the tongue and lingual papillae of the mountain lion (puma). The tongues of three adult male pumas were used in this study. The tongues were dissected and studied firstly by gross and stereomicroscopy. Samples of each part were processed by study with scanning electron microscopy.
S. Erdoğan, S. Villar, H. E. König, W. Pérez   +3 more
openaire   +3 more sources

Puma (Puma concolor) predation on tapir (Tapirus terrestris) [PDF]

Biota Neotropica, 2016
The process of forest fragmentation affects mostly top predators, which are more prone to first disappear. Pumas, Puma concolor, are known to have a generalist diet that includes a wide variety of wild and domestic prey species. The capacity of adapting their diet to consuming prey in anthropogenic habitats may be the reason for this species' success ...
Azevedo, Fernando Cesar Cascelli, Canuto, Vagner, Souza, Fernanda, Widmer, Cynthia Elisa   +3 more
openaire   +2 more sources

E2F-1 induces melanoma cell apoptosis via PUMA up-regulation and Bax translocation

BMC Cancer, 2007
Background PUMA is a pro-apoptotic Bcl-2 family member that has been shown to be involved in apoptosis in many cell types. We sought to ascertain whether induction of PUMA plays a crucial role in E2F-1-induced apoptosis in melanoma cells.
Zhou H Sam, Gomez-Gutierrez Jorge G, Bowling Maria T, Dong Yanbin, Hao Hongying, McMasters Kelly M   +5 more
doaj   +1 more source