Results 41 to 50 of about 23,443 (196)

Glucocorticoid Receptor Signaling in Myeloid Cells Orchestrates Inflammation Resolution and Muscle Repair

open access: yesAdvanced Science, EarlyView.
Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo   +11 more
wiley   +1 more source

Uncoupling of PUMA Expression and Apoptosis Contributes to Functional Heterogeneity in Renal Cell Carcinoma — Prognostic and Translational Implications

open access: yesTranslational Oncology, 2015
Renal cell carcinoma (RCC) is characterized by a profound disruption of proapoptotic signaling networks leading to chemo- and radioresistance. A key mediator of DNA damage-induced apoptosis is the BH3-only protein PUMA.
Xiaoguang Zhou   +11 more
doaj   +1 more source

Sliding Mode Control of the PUMA 560 Robot

open access: yes, 2023
The purpose of this article is to present the application of the sliding mode control and investigate its effectiveness when applied to a three-dimensional robotic manipulator model.
Azar, T. A   +9 more
core   +1 more source

Exploiting Ferroelectric and Spintronic Dynamics for Neural Network Computation

open access: yesAdvanced Intelligent Systems, EarlyView.
Ferroelectric and spintronic devices, relying on the control of polarization and magnetization, offer intrinsically fast, durable, energy‐efficient, and low‐latency building blocks for analog in‐memory computing. The hysteretic dynamics of an order parameter are leveraged to provide nonvolatile, multistate memory and nonlinear switching. Brain‐inspired
Dashiell Harrison   +4 more
wiley   +1 more source

The multi-targeted kinase inhibitor sunitinib induces apoptosis in colon cancer cells via PUMA.

open access: yesPLoS ONE, 2012
Constitutive activation of pro-survival kinases has become a promising target of small molecules with an increasing interest in developing multi-targeted agents.
Jing Sun   +8 more
doaj   +1 more source

PUMA Unit Converter

open access: yes, 2013
The PUMA Repository is a collection of Pascal units supporting medical informatics. It contains reusable source code for a wide field of health-care application development. The code includes converting functions for units of measurement (Unit Converter)
Dietrich, Johannes W.   +1 more
core   +1 more source

Energy‐Aware Perturbation Optimization for Memristor‐Array Convolutional Neural Networks

open access: yesAdvanced Intelligent Systems, EarlyView.
Memristor‐array inference becomes more energy efficient when layer inputs are reshaped before computation. Sinusoidal perturbation encoding with dual‐threshold screening reduces active voltage pulses and contracts ADC input‐current ranges, jointly lowering crossbar and peripheral energy while preserving accuracy across hardware MNIST validation, deep ...
Ao Xu   +6 more
wiley   +1 more source

PUMA Survey 1. Insights in societal changes in Austria

open access: yes, 2018
Full edition for scientific use. PUMA Surveys consist of separate modules designed and prepared by different principle investigators. This PUMA Survey consists of three modules.
PUMA
core   +1 more source

Segmental composition and nerve distribution of the brachial plexus in Galictis cuja

open access: yesThe Anatomical Record, EarlyView.
Abstract Galictis cuja is a neotropical mustelid with terrestrial locomotor habits, yet the anatomy of its brachial plexus has remained undescribed. This study characterizes the origin, organization, and distribution of the brachial plexus nerves in 15 adult specimens (30 antimeres).
Natan da Cruz de Carvalho   +6 more
wiley   +1 more source

Platycodin D induces apoptosis through JNK1/AP-1/PUMA pathway in non-small cell lung cancer cells: A new mechanism for an old compound

open access: yesFrontiers in Pharmacology, 2022
Platycodin D, a triterpenoid monomer, has been shown to possess an anti-tumor effect on various types of cancer. Although Platycodin D has been reported to suppress tumorigenesis, the detailed underlying mechanism remains elusive.
Shuntai Chen   +9 more
doaj   +1 more source

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