Results 61 to 70 of about 43,136 (308)

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

Advanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv, Yi Liu, Ning Xu, Xiao Zhang, Yaming Yang, Chengyao Li, Hanhai Mao, Mingyuan Liu, Xiaolei Liu   +8 more
wiley   +1 more source

PUMA Unit Converter

, 2013
The PUMA Repository is a collection of Pascal units supporting medical informatics. It contains reusable source code for a wide field of health-care application development. The code includes converting functions for units of measurement (Unit Converter)
Dietrich, Johannes W., Dietrich, Johannes W. (5476061)   +1 more
core   +1 more source

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

Advanced Science, EarlyView.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv, Xuejie Cai, Yiming Xu, Xingdong Yang, Ruoying Wang, Han Wang, Yixin Bian, Jiawei Xu, Jiao Lu, Lulu Liu, Yingjie Wang, Jibin Song, Bin Feng, Xisheng Weng   +13 more
wiley   +1 more source

PUMA, antiProton unstable matter annihilation

The European Physical Journal A, 2022
AbstractPUMA, antiProton Unstable Matter Annihilation, is a nuclear-physics experiment at CERN aiming at probing the surface properties of stable and rare isotopes by use of low-energy antiprotons. Low-energy antiprotons offer a very unique sensitivity to the neutron and proton densities at the annihilation site, i.e. in the tail of the nuclear density.
Aumann, T., Bartmann, W., Boine-Frankenheim, O., Bouvard, A., Broche, A., Butin, F., Calvet, D., Carbonell, J., Chiggiato, P., De Gersem, H., De Oliveira, R., Dobers, T., Ehm, F., Somoza, J. Ferreira, Fischer, J., Fraser, M., Friedrich, E., Frotscher, A., Gomez-Ramos, M., Grenard, J-L., Hobl, A., Hupin, G., Husson, A., Indelicato, P., Johnston, K., Klink, C., Kubota, Y., Lazauskas, R., Malbrunot-Ettenauer, S., Marsic, N., Mueller, W.FO., Naimi, S., Nakatsuka, N., Necca, R., Neidherr, D., Neyens, G., Obertelli, A., Ono, Y., Pasinelli, S., Paul, N., Pollacco, E.C., Rossi, D., Scheit, H., Schlaich, M., Schmidt, A., Schweikhard, L., Seki, R., Sels, S., Siesling, E., Uesaka, T., Vilen, M., Wada, M., Wienholtz, F., Wycech, S., Zacarias, S.   +54 more
openaire   +1 more source

FOS3D: A Fluorescence‐Enabled Toolkit for Characterizing a Three‐dimensional Osteosarcoma Model

Advanced Science, EarlyView.
FOS3D describes fluorescent (F) osteosarcoma (OS) cells in a tri‐dimensional (3D) model. The study comprises three phases: development, where biofabrication parameters are tuned to achieve cytocompatibility and tumor‐specific mechanical properties in cell‐laden gelatin methacryloyl constructs; validation, where whole‐well fluorescence reading is ...
William Humble, Wiktor Zywicki, Enrico Lucarelli, Ania Naila Guerrieri, Francesca Taraballi, Gianluca Cidonio, Claudia Di Bella, Carmine Onofrillo, Andrea J. O'Connor, Serena Duchi   +9 more
wiley   +1 more source

Fas/FasL mediates NF-κBp65/PUMA-modulated hepatocytes apoptosis via autophagy to drive liver fibrosis

Cell Death and Disease, 2021
Fas/Fas ligand (FasL)-mediated cell apoptosis involves a variety of physiological and pathological processes including chronic hepatic diseases, and hepatocytes apoptosis contributes to the development of liver fibrosis following various causes. However,
Siwei Tan, Xianzhi Liu, Lingjun Chen, Xiaoqin Wu, Li Tao, Xuemei Pan, Shuyan Tan, Huiling Liu, Jie Jiang, Bin Wu   +9 more
doaj   +1 more source

Platycodin D induces apoptosis through JNK1/AP-1/PUMA pathway in non-small cell lung cancer cells: A new mechanism for an old compound

Frontiers in Pharmacology, 2022
Platycodin D, a triterpenoid monomer, has been shown to possess an anti-tumor effect on various types of cancer. Although Platycodin D has been reported to suppress tumorigenesis, the detailed underlying mechanism remains elusive.
Shuntai Chen, Shuntai Chen, Shuntai Chen, Qing Wang, Qing Wang, Sarah Ming, Honggang Zheng, Baojin Hua, Hsin-Sheng Yang, Hsin-Sheng Yang   +9 more
doaj   +1 more source

The Puma, or Mountain Lion

Science, 1896
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openaire   +3 more sources

Response of pumas (Puma concolor) to migration of their primary prey in Patagonia

PLOS ONE, 2017
Large-scale ungulate migrations result in changes in prey availability for top predators and, as a consequence, can alter predator behavior. Migration may include entire populations of prey species, but often prey populations exhibit partial migration with some individuals remaining resident and others migrating.
Maria L. Gelin, Lyn C. Branch, Daniel H. Thornton, Andrés J. Novaro, Matthew J. Gould, Anthony Caragiulo   +5 more
openaire   +5 more sources

PUMA Survey 1. Insights in societal changes in Austria

, 2018
Full edition for scientific use. PUMA Surveys consist of separate modules designed and prepared by different principle investigators. This PUMA Survey consists of three modules.
PUMA
core   +1 more source