ABSTRACT The shift toward chronic management of EGFR‐mutant lung cancer underscores the urgent need to identify molecular features potentially relevant to osimertinib‐associated interstitial lung disease (ILD). This study aimed to investigate candidate molecular mechanisms of this toxicity by integrating putative osimertinib target profiles with ILD ...
Yilin Ye +5 more
wiley +1 more source
Intravenous versus topical lidocaine gel administered at intubation for prevention of peri-extubation airway complications in adults undergoing orthopaedic surgery: protocol for a randomised controlled trial. [PDF]
Wadi Oudah Alkhuraisi H +4 more
europepmc +1 more source
Bairui granules versus Reyanning granules in adults with acute bronchitis: a multicenter, randomized, double-blind, double-dummy, comparative trial. [PDF]
Wu Y +11 more
europepmc +1 more source
Mind the Gap: Predictors of Osteoporosis Treatment Following Fragility Fracture in Parkinsonism
Abstract Background Fracture risk is increased in Parkinson's yet this risk is often not addressed. Objectives Our objective was to study the extent to which osteoporosis was treated, and predictors of treatment in a large representative cohort with parkinsonism.
Katie C. Naylor +2 more
wiley +1 more source
Comparison of alfentanil and sufentanil on extubation-related cough following suspension laryngoscopy surgery: a randomized controlled trial. [PDF]
Wei Q, Li J, Shao C, Tang Y, Yang Y.
europepmc +1 more source
Breathe, Eat, Talk: Three Essential Ingredients to Quality‐of‐Life Outcomes in Movement Disorders
Abstract Background Breathing, eating, and talking (BET) impairments are common yet frequently underrecognized features of movement disorders. Deficits in respiration, swallowing, voice, and speech may emerge early in the course of a disease, adversely affecting safety, participation, and quality of life.
John Dean +16 more
wiley +1 more source
Exploratory Room-Level Acoustic Soundscape Monitoring of Cough-like Events Under Standard and Ventilation-Restricted Pig-Housing Conditions Using Audio Spectrogram Transformer. [PDF]
Sharifuzzaman M +9 more
europepmc +1 more source
Abstract Background Lower urinary tract symptoms (LUTS) are among the most prevalent nonmotor complaints across the parkinsonian spectrum, yet they remain underutilized as diagnostic and management signals in neurology practice. Although prior reviews have characterized disease‐specific patterns of urinary dysfunction, and recent guidelines address ...
Saar Anis +3 more
wiley +1 more source
Chronic Cough Among Primary Care Doctors: Unmet Needs. [PDF]
García-Sanz MT +2 more
europepmc +1 more source
Abstract Background Cerebellar ataxia, neuropathy and vestibular are flexia syndrome (CANVAS) and RFC1‐related disease are most commonly caused by biallelic AAGGG repeat expansions in RFC1. The high population frequency of this expansion compared to the frequency of CANVAS suggests incomplete penetrance.
Xuemin Wang +13 more
wiley +1 more source

