Results 161 to 170 of about 71,972 (342)

Synthetic Approach to Coumarin Derivatives Through C-H Activation [PDF]

open access: yes, 2015
Coumarins are a family of naturally occurring compounds. Coumarin motifs are present in numerous natural products such as dicoumaral, querecetin, geiparvain etc.
Halder, Bipasa
core  

Exploring Linalool‐Based Phytotherapy for Excitatory/Inhibitory Imbalance in Alzheimer's Disease: A Review of Lavender and Cannabis Therapeutic Effects on Sleep, Seizures, and Cognition

open access: yesPhytotherapy Research, EarlyView.
Schematic overview of the proposed neuromodulatory actions of linalool in Alzheimer's disease. Through multi‐target effects on oxidative stress, amyloid aggregation, GABAergic and glutamatergic signaling, linalool may restore excitatory/inhibitory balance.
Ilaria Piccialli   +4 more
wiley   +1 more source

Xanthatin‐13‐(Pyrrolidine‐2‐Carboxylic Acid), a Sesquiterpene Lactone Isolated From Burdock Leaf, Attenuated Aβ25‐35 Toxicity and Memory Deficits in a Pharmacological Mouse Model of Alzheimer's Disease

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a severe form of dementia, which occurrence increases with age and lifestyle conditions. It is characterized by amyloid protein accumulation forming senile plaques, hyperphosphorylated tau protein forming neurofibrillary tangles, neuroinflammation, and oxidative stress, leading to synapse loss and cell death ...
Charlyne Barry‐Simonnet   +10 more
wiley   +1 more source

Pedunculoside Inhibits Hepatocellular Carcinoma Progression by Activating the MAPK Signaling Pathway Through Targeting and Suppressing CDK4

open access: yesPhytotherapy Research, EarlyView.
Pedunculoside targets and suppresses CDK4; consequently, it activates the MAPK pathway and inhibits hepatocellular carcinoma progression. ABSTRACT Hepatocellular carcinoma (HCC) remains a major challenge in cancer prevention and treatment, highlighting the urgent need for effective and low‐toxicity anti‐HCC therapies. Recently, CDK4‐targeted inhibitors
Yang Zhou   +9 more
wiley   +1 more source

Fluorescent Supramolecular Gels Based on D‐Sorbitol Derivatives

open access: yesSmall, EarlyView.
Sugar‐based fluorescent low‐molecular‐weight gelators (LMWGs) DNapS, DBTDS, and MCumS, prepared by a green, scalable route, form supramolecular gels in water, organic, and deep eutectic solvents. MCumS yields solvent‐dependent nanofibrous networks and viscoelastic injectable eutectogels.
Emmanuel Odella   +5 more
wiley   +1 more source

Synthesis and evaluation of thiazolyl coumarin drug conjugates as carbonic anhydrase isozyme inhibitors by using integrated invitro and insilico approaches [PDF]

open access: gold
Atteeque Ahmed   +8 more
openalex   +1 more source

Thermoresponsive Complex Coacervates as Advanced Carriers for Cell‐Laden Liquid‐Core Capsules for Biomedical Applications

open access: yesSmall, EarlyView.
A thermoresponsive complex coacervate is engineered to transport liquid‐core capsules loaded with human adipose‐derived stem cells, forming modular, hierarchically organized tissue‐forming units. This injectable platform enables precise spatial control while maintaining high cell viability, offering a versatile and bioinspired strategy for minimally ...
Luís P. G. Monteiro   +5 more
wiley   +1 more source

A novel sulfur‐containing photoinitiator based on benzophenone derivatives for rapid photopolymerization

open access: yesSmart Molecules, EarlyView.
This study develops a series of unimolecular photoinitiators, BP‐S1‐5, by incorporating hydrogen‐donating groups into a benzophenone framework. This method reduces the reliance on co‐initiators, and enables BP‐S1‐5 with efficient photoinitiation and excellent molding capability.
Yu Li   +11 more
wiley   +1 more source

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