Results 191 to 200 of about 24,198 (212)

Imperatorin ameliorates myocardial ischemia‐reperfusion injury by inhibiting endoplasmic reticulum stress‐mediated apoptosis via the PI3K/AKT/Nrf2 pathway

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
By activating the PI3K/AKT/Nrf2 pathway, imperatorin can reduce endoplasmic reticulum stress and its mediated apoptosis in cardiomyocytes, improve the pathological changes of myocardial tissue, and thus improve myocardial ischemia/reperfusion injury.
Mingjun Han, Fan Yu, Huanhuan Li
wiley   +1 more source

The Wonders of Vanilla: Celebrating the 150th Anniversary of Synthetic Vanillin

open access: yesChemFoodChem, Volume 2, Issue 2, June 2026.
The year 2024 marked the 150th anniversary of the first commercial production of vanillin, one of the world's most cherished flavor ingredients. This review traces vanilla's history from Mesoamerica to modern production methods, examines its composition, the discovery of vanillin and Haarmann's early synthesis compared to modern methods, and highlights
Elisabetta Brenna   +2 more
wiley   +1 more source

Pharmacokinetic Evaluation of a Cinnamon Product on CYP2A6 Substrate Drugs: Application of a Novel Tool Involving the Nicotine Metabolite Ratio

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1485-1493, June 2026.
Cinnamon (Cinnamomum spp.) is used as a culinary spice and dietary supplement. A major constituent, cinnamaldehyde, was previously shown to inactivate cytochrome P450 (CYP) 2A6 in vitro. A mechanistic static model predicted an ~5‐fold increase in the AUC of the CYP2A6 substrates nicotine and letrozole.
Aiden‐Hung P. Nguyen   +8 more
wiley   +1 more source
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Nanoformulations of Coumarins and the Hybrid Molecules of Coumarins with Potential Anticancer Effects

Anti-Cancer Agents in Medicinal Chemistry, 2020
Mükerrem Betul Yerer   +2 more
exaly  

Chromones and coumarins from Skimmia laureola

Phytochemistry, 1987
T K Razdan, S Harkar
exaly  

Natural and Synthetic Coumarins with Effects on Inflammation

Molecules, 2016
Gilbert Kirsch   +2 more
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Coumarins as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies

European Journal of Medicinal Chemistry, 2015
Anuradha Thakur   +2 more
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Synthesis and antifungal activity of coumarins and angular furanocoumarins

Bioorganic and Medicinal Chemistry, 1999
Soroush Sardari   +2 more
exaly  

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