Results 31 to 40 of about 1,504,105 (267)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Timely cancer diagnosis in children and adolescents is important to improving outcomes. We aimed to quantify time to diagnosis and assess variations by patient, demographic and system‐level factors. Procedure We conducted a population‐based study of individuals aged 0–19 years diagnosed with one of 12 cancers from 2010 to 2022 in ...
Callum Mullen +5 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Ewing sarcoma (ES) and rhabdomyosarcoma (RMS) are aggressive malignancies in children and adolescents where metastases impact prognosis. 18F‐fluoro‐2‐deoxy‐d‐glucose positron emission tomography/computed tomography (FDG‐PET/CT) and bone marrow aspirate and trephine biopsies (BMAT) are used to identify disease involvement.
Imogen Andrews +3 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Intragovernmental governance in South Africa - An analysis of recent jurisprudence
Academicus International Scientific JournalIn the South African local government domain, municipalities’ ability to execute legislative and executive powers is vested in municipal councils (section 151(2) of the Constitution of the Republic of South Africa, 1996).
Andreas SJ Karsten +1 more
doaj +1 more source
Путеводитель предпринимателя, 2020 The article discusses the issues and problems in the functioning of the cluster through the establishment of cooperative and mutually beneficial relations between contractors, suppliers of technologies and resources, related enterprises and the ...
L. A. Akhmetov, D. V. Skvirya
doaj
El municipio y la provincia en la Constitución de 1812
Revista de Derecho Político, 2012 El modelo local establecido por la Constitución de Cádiz de 1812 comportó un cambio revolucionario que resquebrajó la organización administrativa del Antiguo Régimen, insertando los órganos de gobierno del municipio y de la provincia en la estructura del
Javier García Fernández
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Katechizm Kościoła Katolickiego ostatnim z dokumentów odnowy soborowej
Colloquia Theologica Ottoniana, 2013 The Second Vatican Council did not pay in full any instrument of catechesis, as it took place at the Council of Trent and Vatican I but many are expressed in the constitutions and decrees were the inspiration for catechetical renewal that Pope Paul VI ...
Andrzej Offmański
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source