Results 51 to 60 of about 6,093,379 (262)
Impact of ocean warming on sustainable fisheries management informs the Ecosystem Approach to Fisheries [PDF]
, 2017 Acknowledgements Serpetti N., Heymans J.J., and Burrows M.T. were funded by the Natural Environment Research Council and Department for Environment, Food and Rural Affairs under the Marine Ecosystems Research Programme (MERP) (grant No.
Baudron, Alan R +6 more
core +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Circular 02/03 : data collection : collection arrangements on learner data [PDF]
, 2002 "This circular is for consultation. It sets out the medium-term strategy of the Learning and Skills Council (the Council) for collecting data on learners and provides details of the proposed content of the Individualised Learner Record for further ...
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Bace1-dependent amyloid processing regulates hypothalamic leptin sensitivity in obese mice [PDF]
, 2018 We thank AstraZeneca for providing AZ-4217, Mark Smith (Imperial College, London) and Yuchio Yanagawa (Gunma University, Maebashi) for VGlut2-GFP and GAD67-GFP tissue, respectively.
Allsop, David J. P. +15 more
core +5 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
European Crime Prevention Network (EUCPN) [PDF]
, 2012 The European Crime Prevention Network (EUCPN) was set up by Council Decision 2009/902/JHA on 30 November 2009 repealing the establishing Council Decision 2001/427/JHA.
Bislev, Maria, Klima, Noel
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Perinatal mental health : preparing the future nursing workforce [PDF]
, 2019 Perinatal mental health (PMH) problems occur during pregnancy and up to a year after giving birth. They can have a significant effect on the mother and family, and can affect the social, emotional and cognitive development of the child.
Health Education England, Tavistock and Portman NHS Foundation Trust +6 more
core +2 more sources
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source