Results 71 to 80 of about 3,313,431 (294)

Other title: September council meeting, progress report

open access: yes, 1959
"September 1959."SEPTEMBER COUNCIL MEETING -- Status of Council Work -- New Proposals Introduced -- COMMITTEE ACTIVITY AND REPORTS -- Charitable, Benevolent and Penal Institutions -- Parole of Inmates of Penal Institutions -- Education -- Educational ...
Kansas Legislature. Legislative Council.
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

ORDER IN COUNCIL. [PDF]

open access: yesThe Lancet
n ...
openaire   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Other title: March Council meeting, progress report

open access: yes, 1962
"March 1962."MARCH COUNCIL MEETING -- Status of Council Work -- New Proposals Introduced -- COMMITTEE ACTIVITY AND REPORTS -- Agriculture and Livestock -- Soil Conservation - Proposal No.
Kansas. Legislature. Legislative Council.
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

THE ROLE OF THE PRESIDENCY IN THE FUNCTIONING OF THE EUROPEAN UNION ROMANIAN PRESIDENCY OF THE EU COUNCIL - CHALLENGES AND OPPORTUNITIES [PDF]

open access: yesChallenges of the Knowledge Society, 2019
This year, for the first time in the history of its membership in the European Union, Romania exercises the rotating presidency of the Council of the European Union.
Dragoș – Adrian BANTAȘ
doaj  

The attitude of the pro-Arian bishops towards the emperor in the period of reception of the Nicene Christology (325-381)

open access: yesVox Patrum, 2014
Sobór Nicejski nie położył kresu kontrowersji ariańskiej. Po soborze nastą­pił długi okres walki o recepcję chrystologii nicejskiej. Kontrowersja stała się przedmiotem zainteresowania cesarza, ponieważ postrzegano ją jako zagrożenie dla jedności ...
Oleksandr Kashchuk
doaj   +1 more source

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