Results 71 to 80 of about 3,313,431 (294)
Other title: September council meeting, progress report
"September 1959."SEPTEMBER COUNCIL MEETING -- Status of Council Work -- New Proposals Introduced -- COMMITTEE ACTIVITY AND REPORTS -- Charitable, Benevolent and Penal Institutions -- Parole of Inmates of Penal Institutions -- Education -- Educational ...
Kansas Legislature. Legislative Council.
core +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Other title: March Council meeting, progress report
"March 1962."MARCH COUNCIL MEETING -- Status of Council Work -- New Proposals Introduced -- COMMITTEE ACTIVITY AND REPORTS -- Agriculture and Livestock -- Soil Conservation - Proposal No.
Kansas. Legislature. Legislative Council.
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
THE ROLE OF THE PRESIDENCY IN THE FUNCTIONING OF THE EUROPEAN UNION ROMANIAN PRESIDENCY OF THE EU COUNCIL - CHALLENGES AND OPPORTUNITIES [PDF]
This year, for the first time in the history of its membership in the European Union, Romania exercises the rotating presidency of the Council of the European Union.
Dragoș – Adrian BANTAȘ
doaj
Sobór Nicejski nie położył kresu kontrowersji ariańskiej. Po soborze nastąpił długi okres walki o recepcję chrystologii nicejskiej. Kontrowersja stała się przedmiotem zainteresowania cesarza, ponieważ postrzegano ją jako zagrożenie dla jedności ...
Oleksandr Kashchuk
doaj +1 more source

