Results 41 to 50 of about 170,384,737 (242)
Consells consultius autonòmics: anàlisi crítica de les darreres reformes [PDF]
Revista d'Estudis Autonòmics i Federals, 2017 This article examines the recent reforms of the Consultative Councils in Spain. Formally, it is divided into two parts. Firstly, this paper examines the recent abolition of the Consultative Councils in Madrid and Extremadura, and the legal reforms that ...
Anna-Maria Pla Boix
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
SRC annual report; State Rehabilitation Council annual report
, 2010 Annual; Report year ends Sept. 30.; Issued by: State Rehabilitation Advisory Council, -2000/2001; by the State Rehabilitation Council, 2001/2002-; Harvested from the web on 3/24 ...
Connecticut. State Rehabilitation Council.
core +1 more source
Revista de Derecho Político, 2018 Resumen: Estudio de la regulación constitucional y normativa del Consejo de Estado español, desde su reconocimiento constitucional en 1978, pasando por la ley orgánica 3/1980, hasta la reforma acaecida por ley orgánica 3/2004, en los ámbitos referidos a ...
José Manuel Vera Santos
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Other title: SRC annual report; Other title: State Rehabilitation Council annual report
, 2015 Annual; Report year ends Sept. 30.; Issued by: State Rehabilitation Advisory Council, -2000/2001; by the State Rehabilitation Council, 2001 ...
Connecticut. State Rehabilitation Council.
core +2 more sources
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source