Results 61 to 70 of about 170,384,737 (242)
Zeszyty Prawnicze, 2016 A PROPOSAL TO ESTABLISH A COUNCIL OF STATE IN POLAND Summary In 2006 Janusz Kochanowski, Poland’s Civil Rights Spokesman, put forward a proposal for the establishment of a council of state.
Marek Krzymkowski
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The establishment and development of the institute of the State Council in the French Fifth Republic
RUDN Journal of Law, 2012 This article is about the history of the emergence, development and modern status of the State Council of France, founded by Napoleon Bonaparte in the beginning of the XIX century.
P A Kucherenko
doaj
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Other title: SRC annual report; Other title: State Rehabilitation Council annual report
, 2013 Annual; Report year ends Sept. 30.; Issued by: State Rehabilitation Advisory Council, -2000/2001; by the State Rehabilitation Council, 2001 ...
Connecticut. State Rehabilitation Council.
core +1 more source
Communiques of the State Environmental Council of Poland
Problemy Ekorozwoju, 2012 The European Environment and Sustainable Development Advisory Councils network (EEAC) granted the organization of its annual plenary session and conference again to the State Environmental Council of Poland (PROS) to be held this time in Wroclaw after ...
Tomasz Winnicki
doaj
Council of State and Territorial Epidemiologists/CDC Surveillance Case Definition for Multisystem Inflammatory Syndrome in Children Associated with SARS-CoV-2 Infection - United States. [PDF]
MMWR Recomm Rep, 2022 Melgar M +11 more
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source