Results 81 to 90 of about 831,009 (303)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Other title: May Council meeting, progress report [PDF]
, 1958 "May 1958."MAY COUNCIL MEETING -- Status of Council Work -- Legislative Committee on Economy and Efficiency - Fourth Interim Report -- COUNCIL ACTION ON PROPOSALS -- Educational Survey - Pro. No. 7 -- Charges for Care in State Hospitals - Pro. No.
Kansas. Legislature. Legislative Council.
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Other title: May Council meeting : progress report [PDF]
, 1947 "May 1947."Kansas. Legislature. Legislative Council. -- Legislation--Kansas. -- Kansas--Politics and government. -- Y 7.4:MAY COUNCIL MEETING -- SUMMARY OF PROGRAM - PROPOSALS -- 1. Pollution of Fresh Water -- 2. Retirement of State and County Employees -
Kansas. Legislature. Legislative Council.
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Other title: March Council meeting : progress report [PDF]
, 1948 "March 1948."MARCH COUNCIL MEETING -- Status of Council Work -- New Proposals Introduced -- Council Action -- COMMITTEE ACTIVITY AND REPORTS -- Assessment and Taxation -- Severance Tax (Proposal 8) -- Tax System of the State (Proposal 14) -- Education --
Kansas. Legislature. Legislative Council.
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Judges’ deadlines, deadlines for public administration and associations
Zbornik Radova Pravnog Fakulteta u Splitu, 2015 In the theory on the activity of the judge in disputes related to exceeding powers, one fundamental principle demands that this activity is ‘beyond time’: the judge examines some past events and objectively seeks whether the administrative act being ...
Daniel Chabanol
doaj
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Other title: November Council meeting, progress report [PDF]
, 1956 "November 1956."FINAL COUNCIL MEETING Page -- BILLS TO BE SUBMITTED TO THE LEGISLATURE -- No. 1 - Workshop for the Blind -- No. 2 - Brand Inspection Areas -- No. 3 - Noxious Weeds Law Amendments -- No. 4 - Returning Nonresidents to Other States -- No. 5 -
Kansas. Legislature. Legislative Council.
core
Zbornik Radova Pravnog Fakulteta u Splitu, 2012 The State Council, after much resistance, has harmonised its legal practice with that of the Strasbourg Court. Today, proceedings before the State Council are based on the provisions of article 1b of the European Convention for the Protection of Human ...
Marc Gjidara
doaj