Results 111 to 120 of about 966,835 (308)
The EU's dialogue on migration, mobility, and security with the Southern Mediterranean: filling the gaps in the global approach to migration. CEPS Liberty and Security in Europe, June 2011 [PDF]
, 2011 Recent events in North Africa and the Mediterranean have had consequences in terms of human mobility, and are putting the foundations and components of EU’s migration policy under strain.
Carrera, Sergio.
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Alma Swan on the Council of EU report
, 2007 Alma Swan, Dancing with words, <em> Optimal Scholarship </em> , November 24, 2007.
openaire +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
The Czech Presidency of the EU Council: No Triumph, No Tragedy
Romanian Journal of European Affairs, 2009 The text firstly briefly introduces the Presidency as an instrument or tool of the decision-making process within the EU. The article further presents the basic potential criteria for evaluating an EU Council Presidency. Then the course of the Czech Presidency is described according to how it dealt with its functions.
Kaniok, Petr, Smekal, Hubert
openaire +2 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
EU BUDGET LA W: THE MAI N DEFINITIO NS AND PRI NCIPLES
Электронное приложение к Российскому юридическому журналу, 2019 The article is devoted to the main definitions and principles of European Union budget law. The EU budget plays a key role in ensuring the effectiveness of EU activities; it finances the functioning of the Union’ institutional system as well as the ...
Topornin Nikolai
doaj
Education, Multiculturalism and the EU Charter of Rights [PDF]
This paper presents an argument in favour of developing a multiculturalism policy for the EU, by reference to the potential role which could be played by the Charter of Fundamental Rights in this respect.
Chloë Wallace, Jo Shaw
core
Politicizing Council decision-making: The effect of EP empowerment [PDF]
, 2009 Research on the intra-institutional consequences of differences in the EU’s inter-institutional rule configurations is rare. This study investigates the effect of the empowerment of the European Parliament (EP) on the active involvement of ministers in ...
Haege, Frank
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source