Results 91 to 100 of about 971,354 (310)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The Politics of Decision Making in the Council of the EU
Politikon: The IAPSS Journal of Political Science, 2015 This paper examines the decision making of the Council of the European Union to gain insight into how consensus decisions emerge and how they change power allocations and influence the behavior of negotiators and voting blocs. It surveys rationalist and non-rationalist accounts of consensus decisions in the Council and concludes that rationalist ...
openaire +4 more sources
The EU Council Presidency: Billboard for the European Integration?
Czech Journal of International Relations, 2008 The EU Council Presidency is considered a very influential and suitable tool for domestic communication of European integration and its agenda. The article analyses the last ten EU Council Presidencies and their impact on public support to the key ...
Petr Kaniok
doaj
Member States as ‘Trustees’ of the Union? The European Union and the Arctic Council. EU Diplomacy Paper 12 / 2017 [PDF]
, 2017 This paper sets out to analyse two elements often overlooked in the literature on the European Union (EU) and international organisations, namely EU representation in the Arctic Council and the duty of sincere cooperation as a tool of EU representation ...
Bjerkem, Johan
core
Disintegration Through Law? [PDF]
, 2016 This is certainly not the most propitious time to publish a Journal on "Law and Integration". It is disintegration, not integration, that seems to be the dominant motive behind the contemporary events in Europe; it is the panacea offered to soothe the ...
Cannizzaro, Vincenzo
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Estimating the costs of gender-based violence in the European Union [PDF]
, 2014 The purpose of the study is to identify and recommend appropriate methodologies to measure the cost of gender-based and intimate partner violence in EU-28 Member States.
European Institute of Gender Equality (EIGE) +2 more
core +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
COUNCIL REGULATION (EU) 2019/1111: NEW PROGRESS IN INTERNATIONAL CHILD ABDUCTIONS [PDF]
Challenges of the Knowledge SocietyCouncil Regulation (EU) 2019/1111, recently entered into force, brought significant progress for EU Member States in the specific area of international child abductions.
Anca Magda VOICULESCU
doaj
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source