Results 141 to 150 of about 169,119 (354)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Reform of the EU Institutions: Implications for the EU’s Performance in Climate Negotiations. CEPS Policy Brief No. 40, September 2003 [PDF]

, 2003
This CEPS Policy Brief assesses the potential impact of the draft Constitutional Treaty of the Convention on the Future of Europe on the way the EU operates in international climate negotiations. Although Treaty revisions in the EU are ultimately decided
Schaik, Louise van, Egenhofer, Christian.   +1 more
core  

Making a Mark—Time Changing Politics from Estonia: An Alternative Idea for the British, Bulgarian and Estonian EU Presidency

Baltic Journal of European studies, 2016
Estonia is famous among politicians for its e-Governance policies. One core ingredient for this progress is the abolishment of outdated technologies and standards as this kind of legacy policy slows down the innovation process.
Fischer Dirk-Hinnerk
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Migration, Borders and Asylum - Trends and Vulnerabilities in EU Policy. CEPS Paperback. July 2005 [PDF]

, 2005
What level of policy convergence has been achieved by EU member states on immigration, borders and asylum? Although this question may sound rather theoretical, in practice it has profound consequences on the everyday life of individuals and the very ...
Balzacq, Thierry, Carrera, Sergio
core  

Consensus and Isolation in the EU Council of Ministers

Journal of European Integration, 2015
When and how are member states in a small minority or isolated position able to prevail in the EU Council of Ministers? The Council is known for its ability to avoid vetoes and votes. However, we lack a causal mechanism that explains how such a consensus is commonly reached.
openaire   +3 more sources

Intersectional discrimination and EU law: Time to revisit Parris

International Journal of Discrimination and the Law
In this article it is argued that the CJEU judgment in Parris needs to be revisited to recognise that intersectional discrimination is covered by the EU anti-discrimination Directives. There are several reasons for this.
Erica Howard
semanticscholar   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Council Regulation of October 2013

, 2013
Council Regulation (EU) of October 15, 2013 conferring specific tasks on the European Central Bank Concerning Policies Relating to the Prudential Supervision of Credit ...
European Union: Council of the European Union
core