Results 41 to 50 of about 99,682 (264)

Reassessing Bone Marrow Aspirate and Trephine Biopsies in Staging for Paediatric and Young Adult Patients With Ewing Sarcoma and Rhabdomyosarcoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ewing sarcoma (ES) and rhabdomyosarcoma (RMS) are aggressive malignancies in children and adolescents where metastases impact prognosis. 18F‐fluoro‐2‐deoxy‐d‐glucose positron emission tomography/computed tomography (FDG‐PET/CT) and bone marrow aspirate and trephine biopsies (BMAT) are used to identify disease involvement.
Imogen Andrews   +3 more
wiley   +1 more source

Refusal to implement European social partners’ agreements: recent practice of the Commission

open access: yesActa Iuris Stetinensis, 2020
European social partner agreements negotiated on the basis of Article 155 TFEU may be implemented at the level of the European Union at the joint request of the parties via a Council decision.
Dagmara Skupień
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The Baltic States Twenty Years after the EU’s “Big Bang” Enlargement: Political, Economic, and Social Transformations [PDF]

open access: yesRomanian Journal of European Affairs
The article offers a unique and comprehensive reflection on the 20-year membership of the Baltic states — Estonia, Latvia, and Lithuania — in the European Union (EU), highlighting the multifaceted impacts of their integration across the political ...
Aleksandra Palkova
doaj  

The Influence of the EU Council Presidency on Public Opinion [PDF]

open access: yesRomanian Journal of European Affairs, 2012
The Presidency of the EU Council is regarded as an influential and useful instrument for domestic political progress of European integration and the issues it brings along.
Petr Kaniok
doaj  

A Performance Assessment of the 2022 Czech Presidency of the Council of the EU: External Security

open access: yesCzech Journal of International Relations, 2023
This contribution to the forum on the Czech Presidency of the Council of the EU (CZ PRES) in 2022 focuses on external security policy issues. It provides a tentative assessment of the legislative agenda, non-legislative deliverables, and relevant ...
Oldřich Bureš
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

open access: yes
Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein   +11 more
wiley   +1 more source

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