Results 51 to 60 of about 103,559 (264)

The Influence of Regional Governments on National Positions in the Council of the EU

open access: yesCzech Journal of International Relations, 2016
In spite of the fact that some EU member states are fully-fledged federations, some are centralized and many lie somewhere in between these two poles, EU perceives its constituent countries as unitary, indivisible actors.
Pavel Dvořák, Markéta Pitrová
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

More on the EU Council conclusions on OA

open access: yes, 2007
Žiga Turk, Council on Scientific Information in the Digital Age: Too Little Too Late, <em> Growth, jobs and more </em> , November 27, 2007.  Turk is the Slovenian minister for growth.  Excerpt: <b> Update </b> (11/29/07). Also see the EurActiv article on Turk&#39;s assessment of the Council conclusions. <b> Update &
openaire   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

THE EUROPEAN COUNCIL AND THE COUNCIL OF THE EU - PAST, PRESENT AND FUTURE

open access: yesMEST Journal, 2014
The European Council and the Council of the European Union are two of the main institutions of the European Union. The first holds the political powers of the organization, being fundamental in its development and deeper integration as all the Treaties need its approval.
openaire   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

An Assessment of the Polish Presidency of the Council Through the Lens of the EU VAT System

open access: yesFinancial Law Review
The Presidency of the Council is a unique event for each member of the European Union. The effectiveness of the presidency is a determinant of the position both in the Union and in the country.
Marek Bełdzikowski
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

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