Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
The Ever-Changing Union: An Introduction to the History, Institutions and Decision-making Processes of the European Union. 2nd Revised Edition. CEPS Paperbacks. April 2011 [PDF]
, 2011 This fully revised, second edition of the Ever-Changing Union provides a concise overview of the EU’s history, institutional structures and decision-making processes.
Egenhofer, Christian +3 more
core
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
Leading Europe during challenging times: the Spanish Presidency of the Council of the European Union. EUMA Papers Vol. 7, No. 1, January 2010 [PDF]
, 2010 Spain assumed the Presidency of the Council of the European Union on January 1, 2010 with a clear and ambitious set of priorities, with the economic recovery being the most pressing one ahead. Spain’s Presidency comes at challenging times for the country,
Gungor, Gaye.
core
Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone +8 more
wiley +1 more source
French Press on the Romanian and Bulgarian Presidency of the European Union [PDF]
CES Working Papers, 2019 Bulgaria and Romania joined the European Union in 2007. For both of them, the taking over of the rotating presidency of the Council of the European Union has represented a crucial moment.
Antoanela-Paula MUREȘAN
doaj
Regional disparities and convergences in the European Union
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2012 This paper analyses the disparities and convergences between 97 regions of the European Union in the period 2000 to 2008. The methodology is based on the Gini coefficient, Disparity Range Coefficient, Average Disparity Range Coefficient, and σ- and β ...
Petr Blížkovský
doaj +1 more source
Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino +25 more
wiley +1 more source
Connected Coalition Formation and Voting Power in the Council of the European Union: An Endogenous Policy Approach. EIPA Working Paper 99/W/05 [PDF]
, 1999 Resorting to political economy approaches, this paper attempts to associate the industrial structure in the European Union (EU) to the coalition formation process between European member states.
Bilal, Sanoussi, Hosli, Madeleine O.
core
Regional disparities and convergences in Asia
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2012 This paper analyses the disparity and convergence between the 10 and 11 countries of ASEAN and the Commonwealth of Independent States (CIS) respectively and the 31 sub-national regions (provinces) in China.The regional disparity levels and trends were ...
Petr Blížkovský
doaj +1 more source