Results 71 to 80 of about 448,314 (304)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Use of resources in special schools = Y defnydd o adnoddau mewn ysgolion arbennig [PDF]
, 2010 While special schools generally make good use of available funds, many councils’ funding and support arrangements do not reflect the changed context in which schools ...
Body, Gillian
core
Conselhos gestores e gestão pública
Ciências Sociais Unisinos, 2006 The article analise the councils in the context of construction of democracy and popular participation. From a historical backtracking of the its presence in public administration in Brazil, the text discusses the changing occurred in such organisms ...
Maria da Glória Gohn
doaj
Kadem Kadın Araştırmaları DergisiThroughout Christian history, councils have played a central role in shaping doctrines and establishing Church discipline. These councils, convened under the authority of male bishops and where only men had a say in determining theological dogma ...
Duygu Mete Doğan
doaj +1 more source
EVOLUTION OF THE ELECTION PROCESS IN STAVROPOL REGION IN THE MIDDLE OF 1920 th
Вестник Северо-Кавказского федерального университета, 2022 By the Author are considered questions of history of Stavropol Territory in the middle of 20 thе years of the XX thе century. Article is devoted the analysis of activity of the Soviet authorities during the considered period.
Ludmila Alexeevna Zvereva
doaj
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Does Competition Increase Economic Efficiency in Swedish County Councils? [PDF]
The Swedish health care system is to a large extent publicly managed by 21 local county councils. During recent years there has been a movement were local county councils have opted to allow more of the production to be performed by alternative producers
Marklund, Per-Olov +2 more
core +1 more source
Councils and forums for participation in social services
Oñati Socio-Legal SeriesThis study seeks to understand the perceptions of professionals in a specific area of public administration such as social services, on one of the most common and widespread participation mechanisms: consultative councils and forums.
Noemi Bergantiños +3 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Local Government Efficiency in Western Australia [PDF]
The State government of Western Australia is currently working through a significant program of local government reform that has as a core objective a reduction in the number of local councils.
Fogarty, James Joseph, Mugera, Amin W.
core +1 more source