Results 101 to 110 of about 1,772,725 (388)
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Conscience is the indestructible core of one’s personal identity and their sense of agency in the world. When it passes judgment against them, it generates inner conflict (i.e., moral injury).
Michele J. DeMarco
doaj +1 more source
Newsletter produced and distributed by the WKU Counseling & Testing ...
WKU Counseling & Testing Center
core +1 more source
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
The Influence of Student Development Services in Articulation Agreements
Articulation agreements are effective tools in providing a seamless transition for students pursuing a degree at institutions of higher learning. It is essential for those involved in developing these functions to identify the developmental needs of the ...
Emily M. Lehning
doaj +1 more source
Counsel and Defense Counsel Immunity [PDF]
The implementation of the immunities of a lawyer and defense counsel in criminal law was long overdue; in the procedural branches of law, the prohibition of their interrogation is, in fact, recognized as axiomatic, established over the centuries, perhaps, from the moment of the more or less formed legal institute.
openaire +2 more sources
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
Self-Awareness Counseling on Quality of Life of Menopausal Women
Background: Counseling interventions are among the available strategies to improve the menopausal quality of life and self-awareness counseling is effective in improving adaptation, self-confidence and quality of life.
Mahshid Seyed Hoshiyar +3 more
doaj
Transition from Tribal College to Four Year University
Native American college stuents face unusual and difficult transitions. This grounded theory study provides an exploration of the issues Native American students face in transferring from tribally controlled colleges to a traditionally white university ...
Cindy Ann Dell +2 more
doaj +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source

