Results 71 to 80 of about 1,804,421 (390)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Comparison between the effects of group-based acceptance and commitment therapy and group-based reality therapy on work-family conflict & psychological well-being of married female staffs [PDF]

open access: yesمجله علمی دانشگاه علوم پزشکی کردستان, 2019
Background and Aim: Administration of the therapy protocols can increase psychological well-being with resultant decrease in the work-family conflict. The purpose of this study was to make a comparison between the effects of group-based acceptance and ...
Hajikaram A, Ghamari M, Amiri Majd M
doaj  

White Counselor Trainees\u27 Racial Identity and Working Alliance Perceptions [PDF]

open access: yes, 1999
Racial identity has been theorized to significantly affect cross-racial counseling relationships (Helms, 1984, 1995). This study examined the direct impact of White racial identity of 124 counselor trainees on working alliance formation in a same-racial ...
Burkard, Alan W.   +3 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Relationship between characteristics (neo and strong) with progress motivation in nursing students

open access: yesJournal of Medical Education and Development, 2015
Introduction: Motivation has a significant role in acquiring knowledge and scientific skills and the role of character is beyond the intelligence in educational success.
H Heydari   +3 more
doaj  

Sustaining Homeownership Through Education and Counseling [PDF]

open access: yes, 2003
This paper addresses a two-fold problem. First, some families are struggling to sustain their home ownership, yet market responses are inadequate.
Mark Wiranowski
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Factors associated with the delivery of specific physical activity advice to patients with non-communicable diseases by primary care physicians in Klang Valley, Malaysia: a cross-sectional study [PDF]

open access: yesMalaysian Family Physician
Introduction: Specific physical activity advice delivered to patients with non-communicable diseases (NCDs) improves physical activity levels and health outcomes.
Hakimah Khani Suhaimi   +2 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

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