Results 71 to 80 of about 279,737 (286)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Systematic literature review of career sustainability informing social cognitive career theory for SDG related skills in higher education

open access: yesDiscover Sustainability
Background Globalization, technological disruption, and sustainability challenges have intensified the need for higher education to ensure career sustainability and long-term success.
Hendra Pribadi   +5 more
doaj   +1 more source

Prioritising career guidance and development services in post-apartheid South Africa

open access: yesAfrican Journal of Career Development, 2020
Career guidance and development services must be viewed as a priority, especially given Africa’s history of colonisation and deprivation where people of colour were viewed essentially as manual labour.
Anthony L. Pillay
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Satisfaction with family life scale: a validity and reliability study in the Turkish context

open access: yesBMC Psychology
Background The family is one of the most important pillars of society. They provide strong feelings of security, emotional support, and belonging. Family health has a significant impact on the welfare of people and society as a whole.
Arzu Taşdelen Karçkay   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Counselling and psychotherapy: a briefing paper

open access: yes, 2003
The publication of The Way Forward in October 2000 and of the Health and Social Care Professionals bill (draft legislation) in October 2002, are an acknowledgement of the growth of the Counselling/Psychotherapy profession.
Irish Association for Counselling and Psychotherapy
core  

The Effectiveness of Collaborative Couple Therapy on Communication Patterns and Intimacy of Couples Referring to Counseling Centers of Behbahan, Iran

open access: yesArmaghane Danesh Bimonthly Journal, 2017
Background and Aim: Intimacy is a key characteristic of marital relationships and is one of the most prominent characteristics of a successful marriage. Communication patterns can also determine marital satisfaction.
M Sodani   +3 more
doaj  

Adolescents’ perceptions of safety in cyberbullying: the role of bystander support and relationship dynamics

open access: yesInternational Journal of Adolescence and Youth
The present study examines the perceptions of 90 adolescents aged 13-17 (Mage = 14.42, SD = 1.33, 55 female) on positive and negative forms of bystander support.
Sara-Zoe Civita   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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