Results 81 to 90 of about 279,737 (286)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
A systematic review of spontaneous recovery in human fear conditioning
Frontiers in Behavioral NeuroscienceSpontaneous recovery is regarded as an experimental analogue of relapse following successful treatment of anxiety and traumatic disorders using exposure therapy.
Joseph Anderson +5 more
doaj +1 more source
Basic communication and counselling skills in the training of doctors
South African Family Practice, 1987 No abstract available.
M.V. Silbert
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Die primêre geneesheer en die infertiele egpaar
South African Family Practice, 1984 No abstract available.
A.D.P. van den Berg
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Traumatised between culture and religion: Women’s stories
HTS Teologiese Studies/Theological Studies, 2012 The majority of churches in South Africa offer some form of healing, be it diaconal, ritual or faith healing. Western and township views on healing differ significantly in terms of the natural and supernatural causes of and cures for illnesses.
Christina Landman
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Weaving many threads: Reflections on data analysis and rigour in arts-based engagement ethnography
Methods in PsychologyThis paper explores the value of Arts Based Engagement Ethnography (ABEE) when working with people from vulnerable or minoritized communities. ABEE is situated at the juncture of social justice theory, arts-based methods, and critical ethnography ...
Rabab Mukred +4 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source